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Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.
Rotroff DM, Wetmore BA, Dix DJ, Ferguson SS, Clewell HJ, Houck KA, Lecluyse EL, Andersen ME, Judson RS, Smith CM, Sochaski MA, Kavlock RJ, Boellmann F, Martin MT, Reif DM, Wambaugh JF, Thomas RS. Rotroff DM, et al. Among authors: judson rs. Toxicol Sci. 2010 Oct;117(2):348-58. doi: 10.1093/toxsci/kfq220. Epub 2010 Jul 16. Toxicol Sci. 2010. PMID: 20639261 Free PMC article.
Using nuclear receptor activity to stratify hepatocarcinogens.
Shah I, Houck K, Judson RS, Kavlock RJ, Martin MT, Reif DM, Wambaugh J, Dix DJ. Shah I, et al. Among authors: judson rs. PLoS One. 2011 Feb 14;6(2):e14584. doi: 10.1371/journal.pone.0014584. PLoS One. 2011. PMID: 21339822 Free PMC article.
Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays.
Wetmore BA, Wambaugh JF, Ferguson SS, Li L, Clewell HJ 3rd, Judson RS, Freeman K, Bao W, Sochaski MA, Chu TM, Black MB, Healy E, Allen B, Andersen ME, Wolfinger RD, Thomas RS. Wetmore BA, et al. Among authors: judson rs. Toxicol Sci. 2013 Apr;132(2):327-46. doi: 10.1093/toxsci/kft012. Epub 2013 Jan 28. Toxicol Sci. 2013. PMID: 23358191
High-throughput models for exposure-based chemical prioritization in the ExpoCast project.
Wambaugh JF, Setzer RW, Reif DM, Gangwal S, Mitchell-Blackwood J, Arnot JA, Joliet O, Frame A, Rabinowitz J, Knudsen TB, Judson RS, Egeghy P, Vallero D, Cohen Hubal EA. Wambaugh JF, et al. Among authors: judson rs. Environ Sci Technol. 2013 Aug 6;47(15):8479-88. doi: 10.1021/es400482g. Epub 2013 Jul 11. Environ Sci Technol. 2013. PMID: 23758710
Development of a consumer product ingredient database for chemical exposure screening and prioritization.
Goldsmith MR, Grulke CM, Brooks RD, Transue TR, Tan YM, Frame A, Egeghy PP, Edwards R, Chang DT, Tornero-Velez R, Isaacs K, Wang A, Johnson J, Holm K, Reich M, Mitchell J, Vallero DA, Phillips L, Phillips M, Wambaugh JF, Judson RS, Buckley TJ, Dary CC. Goldsmith MR, et al. Among authors: judson rs. Food Chem Toxicol. 2014 Mar;65:269-79. doi: 10.1016/j.fct.2013.12.029. Epub 2013 Dec 27. Food Chem Toxicol. 2014. PMID: 24374094
112 results