Selective Btk inhibition by PRN1008/PRN473 blocks human CLEC-2, and PRN473 reduces venous thrombosis formation in mice.
Smith CW, Campos J, Brown HC, Jooss NJ, Ivanova VS, Harbi M, Garcia-Quintanilla L, Jossi S, Perez-Toledo M, Rookes K, Brill A, Theodore LN, Owens T, LaStant J, Foulke MC, Mukai S, Francesco M, Storek M, Hicks A, Langrish C, Nunn PA, Cunningham AF, Chauhan A, Thomas MR, Watson SP, Nicolson PLR.
Smith CW, et al. Among authors: cunningham af.
Blood Adv. 2024 Nov 12;8(21):5557-5570. doi: 10.1182/bloodadvances.2024012713.
Blood Adv. 2024.
PMID: 38968150
Free PMC article.