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Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation.
Pomaville M, Chennakesavalu M, Wang P, Jiang Z, Sun HL, Ren P, Borchert R, Gupta V, Ye C, Ge R, Zhu Z, Brodnik M, Zhong Y, Moore K, Salwen H, George RE, Krajewska M, Chlenski A, Applebaum MA, He C, Cohn SL. Pomaville M, et al. Among authors: he c. Cell Rep. 2024 May 28;43(5):114165. doi: 10.1016/j.celrep.2024.114165. Epub 2024 Apr 30. Cell Rep. 2024. PMID: 38691450 Free PMC article.
m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1.
Xiao L, De Jesus DF, Ju CW, Wei JB, Hu J, DiStefano-Forti A, Tsuji T, Cero C, Männistö V, Manninen SM, Wei S, Ijaduola O, Blüher M, Cypess AM, Pihlajamäki J, Tseng YH, He C, Kulkarni RN. Xiao L, et al. Among authors: he c. Cell Metab. 2024 Oct 1;36(10):2207-2227.e9. doi: 10.1016/j.cmet.2024.08.006. Epub 2024 Sep 9. Cell Metab. 2024. PMID: 39255799
Shroom3-Rock interaction and profibrotic function: Resolving mechanism of an intronic CKD risk allele.
Reghuvaran A, Kumar A, Lin Q, Rajeevan N, Sun Z, Shi H, Barsotti G, Tanvir EM, Pell J, Perincheri S, Wei C, Planoutene M, Eichmann A, Mas V, Zhang W, Das B, Cantley L, Xu L, He CJ, Menon MC. Reghuvaran A, et al. Among authors: he cj. bioRxiv [Preprint]. 2024 Nov 23:2024.11.22.624409. doi: 10.1101/2024.11.22.624409. bioRxiv. 2024. PMID: 39605692 Free PMC article. Preprint.
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