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Biochemical, biomarker, and behavioral characterization of the GrnR493X mouse model of frontotemporal dementia.
Smith DM, Aggarwal G, Niehoff ML, Jones SA, Banerjee S, Farr SA, Nguyen AD. Smith DM, et al. Among authors: farr sa. bioRxiv [Preprint]. 2024 Feb 2:2023.05.27.542495. doi: 10.1101/2023.05.27.542495. bioRxiv. 2024. Update in: Mol Neurobiol. 2024 Nov;61(11):9708-9722. doi: 10.1007/s12035-024-04190-9 PMID: 37398305 Free PMC article. Updated. Preprint.
Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation.
Aggarwal G, Banerjee S, Jones SA, Benchaar Y, Bélanger J, Sévigny M, Smith DM, Niehoff ML, Pavlack M, de Vera IMS, Petkau TL, Leavitt BR, Ling K, Jafar-Nejad P, Rigo F, Morley JE, Farr SA, Dutchak PA, Sephton CF, Nguyen AD. Aggarwal G, et al. Among authors: farr sa. J Biol Chem. 2023 Dec;299(12):105475. doi: 10.1016/j.jbc.2023.105475. Epub 2023 Nov 18. J Biol Chem. 2023. PMID: 37981208 Free PMC article.
Alzheimer Disease.
Morley JE, Farr SA, Nguyen AD. Morley JE, et al. Among authors: farr sa. Clin Geriatr Med. 2018 Nov;34(4):591-601. doi: 10.1016/j.cger.2018.06.006. Epub 2018 Aug 21. Clin Geriatr Med. 2018. PMID: 30336989 Review.
Adropin correlates with aging-related neuropathology in humans and improves cognitive function in aging mice.
Banerjee S, Ghoshal S, Girardet C, DeMars KM, Yang C, Niehoff ML, Nguyen AD, Jayanth P, Hoelscher BA, Xu F, Banks WA, Hansen KM, Zhang J, Candelario-Jalil E, Farr SA, Butler AA. Banerjee S, et al. Among authors: farr sa. NPJ Aging Mech Dis. 2021 Aug 30;7(1):23. doi: 10.1038/s41514-021-00076-5. NPJ Aging Mech Dis. 2021. PMID: 34462439 Free PMC article.
129 results