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Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation.
Aggarwal G, Banerjee S, Jones SA, Benchaar Y, Bélanger J, Sévigny M, Smith DM, Niehoff ML, Pavlack M, de Vera IMS, Petkau TL, Leavitt BR, Ling K, Jafar-Nejad P, Rigo F, Morley JE, Farr SA, Dutchak PA, Sephton CF, Nguyen AD. Aggarwal G, et al. Among authors: smith dm. J Biol Chem. 2023 Dec;299(12):105475. doi: 10.1016/j.jbc.2023.105475. Epub 2023 Nov 18. J Biol Chem. 2023. PMID: 37981208 Free PMC article.
Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society-USA Panel.
Gandhi RT, Landovitz RJ, Sax PE, Smith DM, Springer SA, Günthard HF, Thompson MA, Bedimo RJ, Benson CA, Buchbinder SP, Crabtree-Ramirez BE, Del Rio C, Eaton EF, Eron JJ Jr, Hoy JF, Lehmann C, Molina JM, Jacobsen DM, Saag MS. Gandhi RT, et al. Among authors: smith dm. JAMA. 2024 Dec 1. doi: 10.1001/jama.2024.24543. Online ahead of print. JAMA. 2024. PMID: 39616604
High throughput application of the NanoBiT Biochemical Assay for the discovery of selective inhibitors of the interaction of PI3K-p110α with KRAS.
Ismail M, Davies G, Sproat G, Monteverde T, Tart J, Acebrón-García-de-Eulate M, Gohlke A, Hancock D, Adhikari S, Stefanovic-Barrett S, Smith DM, Flemington V, Gleave-Hanford ES, Holdgate GA, Kettle JG, Downward J. Ismail M, et al. Among authors: smith dm. SLAS Discov. 2024 Nov 27:100197. doi: 10.1016/j.slasd.2024.100197. Online ahead of print. SLAS Discov. 2024. PMID: 39613028 Free article.
Hemochromatosis neural archetype reveals iron disruption in motor circuits.
Loughnan R, Ahern J, Boyle M, Jernigan TL, Hagler DJ Jr, Iversen JR, Frei O, Smith DM, Andreassen O, Zaitlen N, Sugrue L, Thompson WK, Dale A, Schork AJ, Fan CC. Loughnan R, et al. Among authors: smith dm. Sci Adv. 2024 Nov 22;10(47):eadp4431. doi: 10.1126/sciadv.adp4431. Epub 2024 Nov 22. Sci Adv. 2024. PMID: 39576859 Free PMC article.
1,852 results