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Page 1
Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration.
Liu X, Xin DE, Zhong X, Zhao C, Li Z, Zhang L, Dourson AJ, Lee L, Mishra S, Bayat AE, Nicholson E, Seibel WL, Yan B, Mason J, Turner BJ, Gonsalvez DG, Ong W, Chew SY, Ghosh B, Yoon SO, Xin M, He Z, Tchieu J, Wegner M, Nave KA, Franklin RJM, Dutta R, Trapp BD, Hu M, Smith MA, Jankowski MP, Barton SK, He X, Lu QR. Liu X, et al. Among authors: trapp bd. Cell. 2024 May 9;187(10):2465-2484.e22. doi: 10.1016/j.cell.2024.04.005. Epub 2024 May 2. Cell. 2024. PMID: 38701782
BTK regulates microglial function and neuroinflammation in human stem cell models and mouse models of multiple sclerosis.
Gruber RC, Wirak GS, Blazier AS, Lee L, Dufault MR, Hagan N, Chretien N, LaMorte M, Hammond TR, Cheong A, Ryan SK, Macklin A, Zhang M, Pande N, Havari E, Turner TJ, Chomyk A, Christie E, Trapp BD, Ofengeim D. Gruber RC, et al. Among authors: trapp bd. Nat Commun. 2024 Nov 22;15(1):10116. doi: 10.1038/s41467-024-54430-8. Nat Commun. 2024. PMID: 39578444 Free PMC article.
Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis.
Licht-Mayer S, Campbell GR, Mehta AR, McGill K, Symonds A, Al-Azki S, Pryce G, Zandee S, Zhao C, Kipp M, Smith KJ, Baker D, Altmann D, Anderton SM, Kap YS, Laman JD, 't Hart BA, Rodriguez M, Franklin RJM, Chandran S, Lassmann H, Trapp BD, Mahad DJ. Licht-Mayer S, et al. Among authors: trapp bd. Neuropathol Appl Neurobiol. 2023 Feb;49(1):e12851. doi: 10.1111/nan.12851. Epub 2022 Oct 7. Neuropathol Appl Neurobiol. 2023. PMID: 36181265 Free PMC article.
Single-Nucleus RNA-seq of Normal-Appearing Brain Regions in Relapsing-Remitting vs. Secondary Progressive Multiple Sclerosis: Implications for the Efficacy of Fingolimod.
Kihara Y, Zhu Y, Jonnalagadda D, Romanow W, Palmer C, Siddoway B, Rivera R, Dutta R, Trapp BD, Chun J. Kihara Y, et al. Among authors: trapp bd. Front Cell Neurosci. 2022 Jun 17;16:918041. doi: 10.3389/fncel.2022.918041. eCollection 2022. Front Cell Neurosci. 2022. PMID: 35783097 Free PMC article.
Gut microbes impact stroke severity via the trimethylamine N-oxide pathway.
Zhu W, Romano KA, Li L, Buffa JA, Sangwan N, Prakash P, Tittle AN, Li XS, Fu X, Androjna C, DiDonato AJ, Brinson K, Trapp BD, Fischbach MA, Rey FE, Hajjar AM, DiDonato JA, Hazen SL. Zhu W, et al. Among authors: trapp bd. Cell Host Microbe. 2021 Jul 14;29(7):1199-1208.e5. doi: 10.1016/j.chom.2021.05.002. Epub 2021 Jun 16. Cell Host Microbe. 2021. PMID: 34139173 Free PMC article.
248 results