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367 results

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Page 1
Clinical validation of C12FDG as a marker associated with senescence and osteoarthritic phenotypes.
Hambright WS, Duke VR, Goff AD, Goff AW, Minas LT, Kloser H, Gao X, Huard C, Guo P, Lu A, Mitchell J, Mullen M, Su C, Tchkonia T, Espindola Netto JM, Robbins PD, Niedernhofer LJ, Kirkland JL, Bahney CS, Philippon M, Huard J. Hambright WS, et al. Among authors: kirkland jl. Aging Cell. 2024 May;23(5):e14113. doi: 10.1111/acel.14113. Epub 2024 May 6. Aging Cell. 2024. PMID: 38708778 Free PMC article.
Local senolysis in aged mice only partially replicates the benefits of systemic senolysis.
Farr JN, Saul D, Doolittle ML, Kaur J, Rowsey JL, Vos SJ, Froemming MN, Lagnado AB, Zhu Y, Weivoda M, Ikeno Y, Pignolo RJ, Niedernhofer LJ, Robbins PD, Jurk D, Passos JF, LeBrasseur NK, Tchkonia T, Kirkland JL, Monroe DG, Khosla S. Farr JN, et al. Among authors: kirkland jl. J Clin Invest. 2023 Apr 17;133(8):e162519. doi: 10.1172/JCI162519. J Clin Invest. 2023. PMID: 36809340 Free PMC article.
In vitro and in vivo effects of zoledronate on senescence and senescence-associated secretory phenotype markers.
Samakkarnthai P, Saul D, Zhang L, Aversa Z, Doolittle ML, Sfeir JG, Kaur J, Atkinson EJ, Edwards JR, Russell RGG, Pignolo RJ, Kirkland JL, Tchkonia T, Niedernhofer LJ, Monroe DG, LeBrasseur NK, Farr JN, Robbins PD, Khosla S. Samakkarnthai P, et al. Among authors: kirkland jl. bioRxiv [Preprint]. 2023 Feb 24:2023.02.23.529777. doi: 10.1101/2023.02.23.529777. bioRxiv. 2023. Update in: Aging (Albany NY). 2023 May 7;15(9):3331-3355. doi: 10.18632/aging.204701. PMID: 36865244 Free PMC article. Updated. Preprint.
Cellular senescence in skin-related research: Targeted signaling pathways and naturally occurring therapeutic agents.
Dańczak-Pazdrowska A, Gornowicz-Porowska J, Polańska A, Krajka-Kuźniak V, Stawny M, Gostyńska A, Rubiś B, Nourredine S, Ashiqueali S, Schneider A, Tchkonia T, Wyles SP, Kirkland JL, Masternak MM. Dańczak-Pazdrowska A, et al. Among authors: kirkland jl. Aging Cell. 2023 Jun;22(6):e13845. doi: 10.1111/acel.13845. Epub 2023 Apr 11. Aging Cell. 2023. PMID: 37042069 Free PMC article. Review.
A chronic wound model to investigate skin cellular senescence.
Wyles SP, Dashti P, Pirtskhalava T, Tekin B, Inman C, Gomez LS, Lagnado AB, Prata L, Jurk D, Passos JF, Tchkonia T, Kirkland JL. Wyles SP, et al. Among authors: kirkland jl. Aging (Albany NY). 2023 Apr 21;15(8):2852-2862. doi: 10.18632/aging.204667. Epub 2023 Apr 21. Aging (Albany NY). 2023. PMID: 37086260 Free PMC article.
In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers.
Samakkarnthai P, Saul D, Zhang L, Aversa Z, Doolittle ML, Sfeir JG, Kaur J, Atkinson EJ, Edwards JR, Russell GG, Pignolo RJ, Kirkland JL, Tchkonia T, Niedernhofer LJ, Monroe DG, Lebrasseur NK, Farr JN, Robbins PD, Khosla S. Samakkarnthai P, et al. Among authors: kirkland jl. Aging (Albany NY). 2023 May 7;15(9):3331-3355. doi: 10.18632/aging.204701. Epub 2023 May 7. Aging (Albany NY). 2023. PMID: 37154858 Free PMC article.
Interleukin-6 in Patients With Heart Failure and Preserved Ejection Fraction.
Alogna A, Koepp KE, Sabbah M, Espindola Netto JM, Jensen MD, Kirkland JL, Lam CSP, Obokata M, Petrie MC, Ridker PM, Sorimachi H, Tchkonia T, Voors A, Redfield MM, Borlaug BA. Alogna A, et al. Among authors: kirkland jl. JACC Heart Fail. 2023 Nov;11(11):1549-1561. doi: 10.1016/j.jchf.2023.06.031. Epub 2023 Aug 9. JACC Heart Fail. 2023. PMID: 37565977 Free PMC article.
Past and Future Directions for Research on Cellular Senescence.
Zhu Y, Anastasiadis ZP, Espindola Netto JM, Evans T, Tchkonia T, Kirkland JL. Zhu Y, et al. Among authors: kirkland jl. Cold Spring Harb Perspect Med. 2024 Feb 1;14(2):a041205. doi: 10.1101/cshperspect.a041205. Cold Spring Harb Perspect Med. 2024. PMID: 37734865 Review.
Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults With Obesity and Prediabetes in an 18-Week Randomized Controlled Trial.
Justice JN, Leng XI, LeBrasseur NK, Tchkonia T, Kirkland JL, Mitin N, Liu Y, Kritchevsky SB, Nicklas BJ, Ding J. Justice JN, et al. Among authors: kirkland jl. J Gerontol A Biol Sci Med Sci. 2024 Jan 1;79(1):glad214. doi: 10.1093/gerona/glad214. J Gerontol A Biol Sci Med Sci. 2024. PMID: 37738560 Free PMC article. Clinical Trial.
367 results