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PARP14 is pro- and anti-viral host factor that promotes IFN production and affects the replication of multiple viruses.
Parthasarathy S, Saenjamsai P, Hao H, Ferkul A, Pfannenstiel JJ, Suder EL, Bejan DS, Chen Y, Schwarting N, Aikawa M, Muhlberger E, Orozco RC, Sullivan CS, Cohen MS, Davido DJ, Hume AJ, Fehr AR. Parthasarathy S, et al. Among authors: muhlberger e. bioRxiv [Preprint]. 2024 Apr 26:2024.04.26.591186. doi: 10.1101/2024.04.26.591186. bioRxiv. 2024. PMID: 38712082 Free PMC article. Preprint.
The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters.
Miorin L, Mire CE, Ranjbar S, Hume AJ, Huang J, Crossland NA, White KM, Laporte M, Kehrer T, Haridas V, Moreno E, Nambu A, Jangra S, Cupic A, Dejosez M, Abo KA, Tseng AE, Werder RB, Rathnasinghe R, Mutetwa T, Ramos I, de Aja JS, de Alba Rivas CG, Schotsaert M, Corley RB, Falvo JV, Fernandez-Sesma A, Kim C, Rossignol JF, Wilson AA, Zwaka T, Kotton DN, Mühlberger E, García-Sastre A, Goldfeld AE. Miorin L, et al. Among authors: muhlberger e. bioRxiv [Preprint]. 2022 Feb 9:2022.02.08.479634. doi: 10.1101/2022.02.08.479634. bioRxiv. 2022. PMID: 35169796 Free PMC article. Preprint.
CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses.
Jalloh S, Olejnik J, Berrigan J, Nisa A, Suder EL, Akiyama H, Lei M, Tyagi S, Bushkin Y, Mühlberger E, Gummuluru S. Jalloh S, et al. Among authors: muhlberger e. bioRxiv [Preprint]. 2022 Mar 30:2022.03.29.486190. doi: 10.1101/2022.03.29.486190. bioRxiv. 2022. Update in: PLoS Pathog. 2022 Oct 24;18(10):e1010479. doi: 10.1371/journal.ppat.1010479 PMID: 35378756 Free PMC article. Updated. Preprint.
Inhibitors of dihydroorotate dehydrogenase synergize with the broad antiviral activity of 4'-fluorouridine.
Schrell L, Fuchs HL, Dickmanns A, Scheibner D, Olejnik J, Hume AJ, Reineking W, Störk T, Müller M, Graaf-Rau A, Diederich S, Finke S, Baumgärtner W, Mühlberger E, Balkema-Buschmann A, Dobbelstein M. Schrell L, et al. Among authors: muhlberger e. Antiviral Res. 2024 Dec 3;233:106046. doi: 10.1016/j.antiviral.2024.106046. Online ahead of print. Antiviral Res. 2024. PMID: 39638153 Free article.
Marburg Virus Minigenome Assays.
Suder EL, Scoon WA, Mühlberger E. Suder EL, et al. Among authors: muhlberger e. Methods Mol Biol. 2025;2877:129-139. doi: 10.1007/978-1-0716-4256-6_9. Methods Mol Biol. 2025. PMID: 39585618
137 results