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Page 1
Melanoma clonal subline analysis uncovers heterogeneity-driven immunotherapy resistance mechanisms.
Gruen C, Yang HH, Sassano A, Wu E, Gopalan V, Marie KL, Castro A, Mehrabadi FR, Wu CH, Church I, Needle GA, Smith C, Chin S, Ebersole J, Marcelus C, Fon A, Liu H, Malikic S, Sahinalp C, Carter H, Hannenhalli S, Day CP, Lee MP, Merlino G, Pérez-Guijarro E. Gruen C, et al. Among authors: sahinalp c. bioRxiv [Preprint]. 2023 Apr 5:2023.04.03.535074. doi: 10.1101/2023.04.03.535074. bioRxiv. 2023. PMID: 37333132 Free PMC article. Preprint.
Severus: accurate detection and characterization of somatic structural variation in tumor genomes using long reads.
Keskus A, Bryant A, Ahmad T, Yoo B, Aganezov S, Goretsky A, Donmez A, Lansdon LA, Rodriguez I, Park J, Liu Y, Cui X, Gardner J, McNulty B, Sacco S, Shetty J, Zhao Y, Tran B, Narzisi G, Helland A, Cook DE, Chang PC, Kolesnikov A, Carroll A, Molloy EK, Pushel I, Guest E, Pastinen T, Shafin K, Miga KH, Malikic S, Day CP, Robine N, Sahinalp C, Dean M, Farooqi MS, Paten B, Kolmogorov M. Keskus A, et al. Among authors: sahinalp c. medRxiv [Preprint]. 2024 Mar 26:2024.03.22.24304756. doi: 10.1101/2024.03.22.24304756. medRxiv. 2024. PMID: 38585974 Free PMC article. Preprint.
How has the AI boom impacted algorithmic biology?
Singh M, Sahinalp C, Zeng J, Li WV, Kingsford C, Zhang Q, Przytycka T, Welch J, Ma J, Berger B. Singh M, et al. Among authors: sahinalp c. Cell Syst. 2024 Jun 19;15(6):483-487. doi: 10.1016/j.cels.2024.05.008. Cell Syst. 2024. PMID: 38901402
Big data in basic and translational cancer research.
Jiang P, Sinha S, Aldape K, Hannenhalli S, Sahinalp C, Ruppin E. Jiang P, et al. Among authors: sahinalp c. Nat Rev Cancer. 2022 Nov;22(11):625-639. doi: 10.1038/s41568-022-00502-0. Epub 2022 Sep 5. Nat Rev Cancer. 2022. PMID: 36064595 Free PMC article. Review.
CYP2C8, CYP2C9, and CYP2C19 Characterization Using Next-Generation Sequencing and Haplotype Analysis: A GeT-RM Collaborative Project.
Gaedigk A, Boone EC, Scherer SE, Lee SB, Numanagić I, Sahinalp C, Smith JD, McGee S, Radhakrishnan A, Qin X, Wang WY, Farrow EG, Gonzaludo N, Halpern AL, Nickerson DA, Miller NA, Pratt VM, Kalman LV. Gaedigk A, et al. Among authors: sahinalp c. J Mol Diagn. 2022 Apr;24(4):337-350. doi: 10.1016/j.jmoldx.2021.12.011. Epub 2022 Feb 5. J Mol Diagn. 2022. PMID: 35134542 Free PMC article.
Proteogenomic Analysis Unveils the HLA Class I-Presented Immunopeptidome in Melanoma and EGFR-Mutant Lung Adenocarcinoma.
Qi YA, Maity TK, Cultraro CM, Misra V, Zhang X, Ade C, Gao S, Milewski D, Nguyen KD, Ebrahimabadi MH, Hanada KI, Khan J, Sahinalp C, Yang JC, Guha U. Qi YA, et al. Among authors: sahinalp c. Mol Cell Proteomics. 2021;20:100136. doi: 10.1016/j.mcpro.2021.100136. Epub 2021 Aug 13. Mol Cell Proteomics. 2021. PMID: 34391887 Free PMC article.
Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer.
Roper N, Brown AL, Wei JS, Pack S, Trindade C, Kim C, Restifo O, Gao S, Sindiri S, Mehrabadi F, El Meskini R, Ohler ZW, Maity TK, Venugopalan A, Cultraro CM, Akoth E, Padiernos E, Chen H, Kesarwala A, Smart DK, Nilubol N, Rajan A, Piotrowska Z, Xi L, Raffeld M, Panchenko AR, Sahinalp C, Hewitt S, Hoang CD, Khan J, Guha U. Roper N, et al. Among authors: sahinalp c. Cell Rep Med. 2020 Apr 21;1(1):100007. doi: 10.1016/j.xcrm.2020.100007. Cell Rep Med. 2020. PMID: 32483558 Free PMC article. Clinical Trial.
A community effort to create standards for evaluating tumor subclonal reconstruction.
Salcedo A, Tarabichi M, Espiritu SMG, Deshwar AG, David M, Wilson NM, Dentro S, Wintersinger JA, Liu LY, Ko M, Sivanandan S, Zhang H, Zhu K, Ou Yang TH, Chilton JM, Buchanan A, Lalansingh CM, P'ng C, Anghel CV, Umar I, Lo B, Zou W; DREAM SMC-Het Participants; Simpson JT, Stuart JM, Anastassiou D, Guan Y, Ewing AD, Ellrott K, Wedge DC, Morris Q, Van Loo P, Boutros PC. Salcedo A, et al. Nat Biotechnol. 2020 Jan;38(1):97-107. doi: 10.1038/s41587-019-0364-z. Epub 2020 Jan 9. Nat Biotechnol. 2020. PMID: 31919445 Free PMC article.
26 results