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Page 1
Mapping genotypes to chromatin accessibility profiles in single cells.
Izzo F, Myers RM, Ganesan S, Mekerishvili L, Kottapalli S, Prieto T, Eton EO, Botella T, Dunbar AJ, Bowman RL, Sotelo J, Potenski C, Mimitou EP, Stahl M, El Ghaity-Beckley S, Arandela J, Raviram R, Choi DC, Hoffman R, Chaligné R, Abdel-Wahab O, Smibert P, Ghobrial IM, Scandura JM, Marcellino B, Levine RL, Landau DA. Izzo F, et al. Among authors: smibert p. Nature. 2024 May;629(8014):1149-1157. doi: 10.1038/s41586-024-07388-y. Epub 2024 May 8. Nature. 2024. PMID: 38720070
Somatic mutations and cell identity linked by Genotyping of Transcriptomes.
Nam AS, Kim KT, Chaligne R, Izzo F, Ang C, Taylor J, Myers RM, Abu-Zeinah G, Brand R, Omans ND, Alonso A, Sheridan C, Mariani M, Dai X, Harrington E, Pastore A, Cubillos-Ruiz JR, Tam W, Hoffman R, Rabadan R, Scandura JM, Abdel-Wahab O, Smibert P, Landau DA. Nam AS, et al. Among authors: smibert p. Nature. 2019 Jul;571(7765):355-360. doi: 10.1038/s41586-019-1367-0. Epub 2019 Jul 3. Nature. 2019. PMID: 31270458 Free PMC article.
Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells.
Mimitou EP, Lareau CA, Chen KY, Zorzetto-Fernandes AL, Hao Y, Takeshima Y, Luo W, Huang TS, Yeung BZ, Papalexi E, Thakore PI, Kibayashi T, Wing JB, Hata M, Satija R, Nazor KL, Sakaguchi S, Ludwig LS, Sankaran VG, Regev A, Smibert P. Mimitou EP, et al. Among authors: smibert p. Nat Biotechnol. 2021 Oct;39(10):1246-1258. doi: 10.1038/s41587-021-00927-2. Epub 2021 Jun 3. Nat Biotechnol. 2021. PMID: 34083792 Free PMC article.
Characterizing cellular heterogeneity in chromatin state with scCUT&Tag-pro.
Zhang B, Srivastava A, Mimitou E, Stuart T, Raimondi I, Hao Y, Smibert P, Satija R. Zhang B, et al. Among authors: smibert p. Nat Biotechnol. 2022 Aug;40(8):1220-1230. doi: 10.1038/s41587-022-01250-0. Epub 2022 Mar 24. Nat Biotechnol. 2022. PMID: 35332340 Free PMC article.
A genome-scale screen for synthetic drivers of T cell proliferation.
Legut M, Gajic Z, Guarino M, Daniloski Z, Rahman JA, Xue X, Lu C, Lu L, Mimitou EP, Hao S, Davoli T, Diefenbach C, Smibert P, Sanjana NE. Legut M, et al. Among authors: smibert p. Nature. 2022 Mar;603(7902):728-735. doi: 10.1038/s41586-022-04494-7. Epub 2022 Mar 16. Nature. 2022. PMID: 35296855 Free PMC article.
Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells.
Lareau CA, Dubois SM, Buquicchio FA, Hsieh YH, Garg K, Kautz P, Nitsch L, Praktiknjo SD, Maschmeyer P, Verboon JM, Gutierrez JC, Yin Y, Fiskin E, Luo W, Mimitou EP, Muus C, Malhotra R, Parikh S, Fleming MD, Oevermann L, Schulte J, Eckert C, Kundaje A, Smibert P, Vardhana SA, Satpathy AT, Regev A, Sankaran VG, Agarwal S, Ludwig LS. Lareau CA, et al. Among authors: smibert p. Nat Genet. 2023 Jul;55(7):1198-1209. doi: 10.1038/s41588-023-01433-8. Epub 2023 Jun 29. Nat Genet. 2023. PMID: 37386249 Free PMC article.
50 results