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Page 1
Risk loci involved in giant cell arteritis susceptibility: a genome-wide association study.
Borrego-Yaniz G, Ortiz-Fernández L, Madrid-Paredes A, Kerick M, Hernández-Rodríguez J, Mackie SL, Vaglio A, Castañeda S, Solans R, Mestre-Torres J, Khalidi N, Langford CA, Ytterberg S, Beretta L, Govoni M, Emmi G, Cimmino MA, Witte T, Neumann T, Holle J, Schönau V, Pugnet G, Papo T, Haroche J, Mahr A, Mouthon L, Molberg Ø, Diamantopoulos AP, Voskuyl A, Daikeler T, Berger CT, Molloy ES, Blockmans D, van Sleen Y, Iles M, Sorensen L, Luqmani R, Reynolds G, Bukhari M, Bhagat S, Ortego-Centeno N, Brouwer E, Lamprecht P, Klapa S, Salvarani C, Merkel PA, Cid MC, González-Gay MA, Morgan AW, Martin J, Márquez A; Spanish GCA Group; UK GCA Consortium; Vasculitis Clinical Research Consortium. Borrego-Yaniz G, et al. Among authors: ortego centeno n. Lancet Rheumatol. 2024 Jun;6(6):e374-e383. doi: 10.1016/S2665-9913(24)00064-X. Epub 2024 May 8. Lancet Rheumatol. 2024. PMID: 38734017 Free PMC article.
Identification of Mechanisms by Which Genetic Susceptibility Loci Influence Systemic Sclerosis Risk Using Functional Genomics in Primary T Cells and Monocytes.
González-Serna D, Shi C, Kerick M, Hankinson J, Ding J, McGovern A, Tutino M, Villanueva-Martin G, Ortego-Centeno N, Callejas JL, Martin J, Orozco G. González-Serna D, et al. Arthritis Rheumatol. 2023 Jun;75(6):1007-1020. doi: 10.1002/art.42396. Epub 2023 Apr 9. Arthritis Rheumatol. 2023. PMID: 36281738 Free PMC article.
Single-cell transcriptomic profiling reveals a pathogenic role of cytotoxic CD4+ T cells in giant cell arteritis.
Carmona EG, Callejas-Rubio JL, Raya E, Ríos-Fernández R, Villanueva-Martín G, Cid MC, Hernández-Rodríguez J, Ballestar E, Timmermann B, Ortego-Centeno N, Martín J, Márquez A. Carmona EG, et al. Among authors: ortego centeno n. J Autoimmun. 2024 Jan;142:103124. doi: 10.1016/j.jaut.2023.103124. Epub 2023 Nov 11. J Autoimmun. 2024. PMID: 37952293 Free article.
Cranial and extracranial giant cell arteritis do not exhibit differences in the IL6 -174 G/C gene polymorphism.
Genre F, Prieto-Peña D, Pulito-Cueto V, Ocejo-Vinyals JG, Atienza-Mateo B, Muñoz Jiménez A, Ortiz-Sanjuán F, Romero-Yuste S, Moriano C, Galíndez-Agirregoikoa E, Calvo I, Ortego Centeno N, Álvarez-Rivas N, Miranda-Filloy JA, Llorente I, Blanco R, Gualillo O, Martín J, Castañeda S, López-Mejías R, Remuzgo-Martínez S, González-Gay MA. Genre F, et al. Clin Exp Rheumatol. 2023 Apr;41(4):910-915. doi: 10.55563/clinexprheumatol/cbjnmo. Epub 2023 Mar 2. Clin Exp Rheumatol. 2023. PMID: 36912345 Free article.
Cranial and extracranial large-vessel giant cell arteritis share a genetic pattern of interferon-gamma pathway.
Prieto-Peña D, Genre F, Pulito-Cueto V, Ocejo-Vinyals JG, Atienza-Mateo B, Muñoz Jiménez A, Ortiz-Sanjuán F, Romero-Yuste S, Moriano C, Galindez-Agirregoikoa E, Calvo I, Ortego Centeno N, Álvarez-Rivas N, Miranda-Filloy JA, Baldivieso-Achá JP, Blanco R, Gualillo O, Martín J, Castañeda S, López-Mejías R, Remuzgo-Martínez S, González-Gay MA. Prieto-Peña D, et al. Clin Exp Rheumatol. 2023 Apr;41(4):864-869. doi: 10.55563/clinexprheumatol/3cqh12. Epub 2022 Dec 5. Clin Exp Rheumatol. 2023. PMID: 36533991 Free article.
Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis.
Ortiz-Fernández L, Carmona FD, López-Mejías R, González-Escribano MF, Lyons PA, Morgan AW, Sawalha AH, Merkel PA, Smith KGC, González-Gay MA, Martín J; Spanish GCA Study Group, UK GCA Consortium, Turkish Takayasu Study Group, Vasculitis Clinical Research Consortium, IgAV Study Group, AAV Study group. Ortiz-Fernández L, et al. Ann Rheum Dis. 2018 Apr;77(4):589-595. doi: 10.1136/annrheumdis-2017-212372. Epub 2018 Jan 27. Ann Rheum Dis. 2018. PMID: 29374629 Free PMC article.
Influence of the IL6 gene in susceptibility to systemic sclerosis.
Cénit MC, Simeón CP, Vonk MC, Callejas-Rubio JL, Espinosa G, Carreira P, Blanco FJ, Narvaez J, Tolosa C, Román-Ivorra JA, Gómez-García I, García-Hernández FJ, Gallego M, García-Portales R, Egurbide MV, Fonollosa V, García de la Peña P, López-Longo FJ, González-Gay MA; Spanish Scleroderma Group; Hesselstrand R, Riemekasten G, Witte T, Voskuyl AE, Schuerwegh AJ, Madhok R, Fonseca C, Denton C, Nordin A, Palm Ø, van Laar JM, Hunzelmann N, Distler JH, Kreuter A, Herrick A, Worthington J, Koeleman BP, Radstake TR, Martín J. Cénit MC, et al. J Rheumatol. 2012 Dec;39(12):2294-302. doi: 10.3899/jrheum.120506. Epub 2012 Oct 1. J Rheumatol. 2012. PMID: 23027890
Confirmation of association of the macrophage migration inhibitory factor gene with systemic sclerosis in a large European population.
Bossini-Castillo L, Simeon CP, Beretta L, Vonk MC, Callejas-Rubio JL, Espinosa G, Carreira P, Camps MT, Rodríguez-Rodríguez L, Rodríguez-Carballeira M, García-Hernández FJ, López-Longo FJ, Hernández-Hernández V, Sáez-Comet L, Egurbide MV, Hesselstrand R, Nordin A, Hoffmann-Vold AM, Vanthuyne M, Smith V, De Langhe E, Kreuter A, Riemekasten G, Witte T, Hunzelmann N, Voskuyl AE, Schuerwegh AJ, Lunardi C, Airó P, Scorza R, Shiels P, van Laar JM, Fonseca C, Denton C, Herrick A, Worthington J, Koeleman BP, Rueda B, Radstake TR, Martin J; Spanish Scleroderma Group. Bossini-Castillo L, et al. Rheumatology (Oxford). 2011 Nov;50(11):1976-81. doi: 10.1093/rheumatology/ker259. Epub 2011 Aug 28. Rheumatology (Oxford). 2011. PMID: 21875883
Confirmation of CCR6 as a risk factor for anti-topoisomerase I antibodies in systemic sclerosis.
Ochoa E, Martin JE, Assasi S, Beretta L, Carreira P, Guillén A, Simeón CP, Koumakis E, Dieude P, Allanore Y, García-Hernández FJ, Espinosa G, Castellví I, Trapiella JL, Rodriguez L, González-Gay MÁ, Egurbide MV, Sáez L, Callejas-Rubio JL, Vargas-Hitos JA, Hunzelmann N, Riemekasten G, Witte T, Distler JH, Kreuter A, Lunardi C, Santaniello A, Tan FK, Shiels PG, Herrick A, Worthington J, Vonk MC, Koeleman BP, Radstake TR, Mayes MD, Martin J; Spanish Scleroderma Group. Ochoa E, et al. Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 91):S31-5. Epub 2015 Aug 27. Clin Exp Rheumatol. 2015. PMID: 26314374
387 results