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Inhibition of de novo ceramide synthesis by sirtuin-1 improves beta-cell function and glucose metabolism in type 2 diabetes.
Velagapudi S, Karsai G, Karsai M, Mohammed SA, Montecucco F, Liberale L, Lee H, Carbone F, Adami GF, Yang K, Crucet M, Stein S, Paneni F, Lapikova-Bryhinska T, Jang HD, Kraler S, Vdovenko D, Züllig RA, Camici GG, Kim HS, Laaksonen R, Gerber PA, Hornemann T, Akhmedov A, Lüscher TF. Velagapudi S, et al. Among authors: lee h. Cardiovasc Res. 2024 Sep 21;120(11):1265-1278. doi: 10.1093/cvr/cvae100. Cardiovasc Res. 2024. PMID: 38739545
Cyclase-associated protein 1 is a binding partner of proprotein convertase subtilisin/kexin type-9 and is required for the degradation of low-density lipoprotein receptors by proprotein convertase subtilisin/kexin type-9.
Jang HD, Lee SE, Yang J, Lee HC, Shin D, Lee H, Lee J, Jin S, Kim S, Lee SJ, You J, Park HW, Nam KY, Lee SH, Park SW, Kim JS, Kim SY, Kwon YW, Kwak SH, Yang HM, Kim HS. Jang HD, et al. Among authors: lee sh, lee sj, lee h, lee hc, lee j, lee se. Eur Heart J. 2020 Jan 7;41(2):239-252. doi: 10.1093/eurheartj/ehz566. Eur Heart J. 2020. PMID: 31419281 Free PMC article.
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