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Construction of a screening system for lipid-derived radical inhibitors and validation of hit compounds to target retinal and cerebrovascular diseases.
Mori R, Abe M, Saimoto Y, Shinto S, Jodai S, Tomomatsu M, Tazoe K, Ishida M, Enoki M, Kato N, Yamashita T, Itabashi Y, Nakanishi I, Ohkubo K, Kaidzu S, Tanito M, Matsuoka Y, Morimoto K, Yamada KI. Mori R, et al. Among authors: yamashita t. Redox Biol. 2024 Jul;73:103186. doi: 10.1016/j.redox.2024.103186. Epub 2024 May 8. Redox Biol. 2024. PMID: 38744193 Free PMC article.
New high-throughput screening detects compounds that suppress pancreatic stellate cell activation and attenuate pancreatic cancer growth.
Sagara A, Nakata K, Yamashita T, Guan W, Zhong P, Matsumoto S, Endo S, Iwamoto C, Shindo K, Ikenaga N, Moriyama T, Ohuchida K, Mizumoto K, Nakamura M. Sagara A, et al. Among authors: yamashita t. Pancreatology. 2021 Apr 20:S1424-3903(21)00141-1. doi: 10.1016/j.pan.2021.04.002. Online ahead of print. Pancreatology. 2021. PMID: 33965328
Inhibition of G protein-coupled receptor 68 using homoharringtonine attenuates chronic kidney disease-associated cardiac impairment.
Yoshida Y, Fukuoka K, Sakugawa M, Kurogi M, Hamamura K, Hamasaki K, Tsurusaki F, Sotono K, Nishi T, Fukuda T, Kumamoto T, Oyama K, Ogino T, Tsuruta A, Mayanagi K, Yamashita T, Fuchino H, Kawahara N, Yoshimatsu K, Kawakami H, Koyanagi S, Matsunaga N, Ohdo S. Yoshida Y, et al. Among authors: yamashita t. Transl Res. 2024 Jul;269:31-46. doi: 10.1016/j.trsl.2024.02.004. Epub 2024 Feb 23. Transl Res. 2024. PMID: 38401836
Combinatorial screening for therapeutics in ATTRv amyloidosis identifies naphthoquinone analogues as TTR-selective amyloid disruptors.
Sasaki R, Suico MA, Chosa K, Teranishi Y, Sato T, Kagami A, Kotani S, Kato H, Hitora Y, Tsukamoto S, Yamashita T, Yokoyama T, Mizuguchi M, Kai H, Shuto T. Sasaki R, et al. Among authors: yamashita t. J Pharmacol Sci. 2023 Jan;151(1):54-62. doi: 10.1016/j.jphs.2022.11.004. Epub 2022 Nov 29. J Pharmacol Sci. 2023. PMID: 36522123 Free article.
6,899 results