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Human iPSC-derived MSCs induce neurotrophic effects and improve metabolic activity in acute neuronal injury models.
Kawatani K, Omana Suarez G, Perkerson RB 3rd, Parent EE, Nambara T, Knight JA, Parsons TM, Gupta K, Shue F, Alnobani A, Vibhute P, Cai H, Guerrero-Cázares H, Copland JA 3rd, Quiñones-Hinojosa A, Kanekiyo T. Kawatani K, et al. Among authors: kanekiyo t. J Neurosci. 2024 Nov 4:e0606242024. doi: 10.1523/JNEUROSCI.0606-24.2024. Online ahead of print. J Neurosci. 2024. PMID: 39496487
Modeling Lewy body disease with SNCA triplication iPSC-derived cortical organoids and identifying therapeutic drugs.
Jin Y, Li F, Li Z, Ikezu TC, O'Leary J, Selvaraj M, Zhu Y, Martens YA, Koga S, Santhakumar H, Li Y, Lu W, You Y, Lolo K, DeTure M, Beasley AI, Davis MD, McLean PJ, Ross OA, Kanekiyo T, Ikezu T, Caulfield T, Carr J, Wszolek ZK, Bu G, Dickson DW, Zhao N. Jin Y, et al. Among authors: kanekiyo t. Sci Adv. 2024 Sep 13;10(37):eadk3700. doi: 10.1126/sciadv.adk3700. Epub 2024 Sep 11. Sci Adv. 2024. PMID: 39259788 Free PMC article.
ABCA7-dependent induction of neuropeptide Y is required for synaptic resilience in Alzheimer's disease through BDNF/NGFR signaling.
Tayran H, Yilmaz E, Bhattarai P, Min Y, Wang X, Ma Y, Wang N, Jeong I, Nelson N, Kassara N, Cosacak MI, Dogru RM, Reyes-Dumeyer D, Stenersen JM, Reddy JS, Qiao M, Flaherty D, Gunasekaran TI, Yang Z, Jurisch-Yaksi N, Teich AF, Kanekiyo T, Tosto G, Vardarajan BN, İş Ö, Ertekin-Taner N, Mayeux R, Kizil C. Tayran H, et al. Among authors: kanekiyo t. Cell Genom. 2024 Sep 11;4(9):100642. doi: 10.1016/j.xgen.2024.100642. Epub 2024 Aug 30. Cell Genom. 2024. PMID: 39216475 Free PMC article.
Secretome from iPSC-derived MSCs exerts proangiogenic and immunosuppressive effects to alleviate radiation-induced vascular endothelial cell damage.
Gupta K, Perkerson RB 3rd, Parsons TM, Angom R, Amerna D, Burgess JD, Ren Y, McLean PJ, Mukhopadhyay D, Vibhute P, Wszolek ZK, Zubair AC, Quiñones-Hinojosa A, Kanekiyo T. Gupta K, et al. Among authors: kanekiyo t. Stem Cell Res Ther. 2024 Jul 29;15(1):230. doi: 10.1186/s13287-024-03847-5. Stem Cell Res Ther. 2024. PMID: 39075600 Free PMC article.
Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference.
Kloske CM, Belloy ME, Blue EE, Bowman GR, Carrillo MC, Chen X, Chiba-Falek O, Davis AA, Paolo GD, Garretti F, Gate D, Golden LR, Heinecke JW, Herz J, Huang Y, Iadecola C, Johnson LA, Kanekiyo T, Karch CM, Khvorova A, Koppes-den Hertog SJ, Lamb BT, Lawler PE, Guen YL, Litvinchuk A, Liu CC, Mahinrad S, Marcora E, Marino C, Michaelson DM, Miller JJ, Morganti JM, Narayan PS, Naslavsky MS, Oosthoek M, Ramachandran KV, Ramakrishnan A, Raulin AC, Robert A, Saleh RNM, Sexton C, Shah N, Shue F, Sible IJ, Soranno A, Strickland MR, Tcw J, Thierry M, Tsai LH, Tuckey RA, Ulrich JD, van der Kant R, Wang N, Wellington CL, Weninger SC, Yassine HN, Zhao N, Bu G, Goate AM, Holtzman DM. Kloske CM, et al. Among authors: kanekiyo t. Alzheimers Dement. 2024 Sep;20(9):6590-6605. doi: 10.1002/alz.13877. Epub 2024 Jul 19. Alzheimers Dement. 2024. PMID: 39031528 Free PMC article. Review.
Gliovascular transcriptional perturbations in Alzheimer's disease reveal molecular mechanisms of blood brain barrier dysfunction.
İş Ö, Wang X, Reddy JS, Min Y, Yilmaz E, Bhattarai P, Patel T, Bergman J, Quicksall Z, Heckman MG, Tutor-New FQ, Can Demirdogen B, White L, Koga S, Krause V, Inoue Y, Kanekiyo T, Cosacak MI, Nelson N, Lee AJ, Vardarajan B, Mayeux R, Kouri N, Deniz K, Carnwath T, Oatman SR, Lewis-Tuffin LJ, Nguyen T; Alzheimer’s Disease Neuroimaging Initiative; Carrasquillo MM, Graff-Radford J, Petersen RC, Jr Jack CR, Kantarci K, Murray ME, Nho K, Saykin AJ, Dickson DW, Kizil C, Allen M, Ertekin-Taner N. İş Ö, et al. Among authors: kanekiyo t. Nat Commun. 2024 Jun 20;15(1):4758. doi: 10.1038/s41467-024-48926-6. Nat Commun. 2024. PMID: 38902234 Free PMC article.
Relationships between PET and blood plasma biomarkers in corticobasal syndrome.
Singh NA, Alnobani A, Graff-Radford J, Machulda MM, Mielke MM, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Kanekiyo T, Josephs KA, Whitwell JL. Singh NA, et al. Among authors: kanekiyo t. Alzheimers Dement. 2024 Jul;20(7):4765-4774. doi: 10.1002/alz.13914. Epub 2024 Jun 17. Alzheimers Dement. 2024. PMID: 38885334 Free PMC article.
114 results