Lin G - Search Results

1

Does glial lipid dysregulation alter sleep in Alzheimer's and Parkinson's disease?

Goodman LD, Moulton MJ, Lin G, Bellen HJ. Goodman LD, et al. Among authors: lin g. Trends Mol Med. 2024 Oct;30(10):913-923. doi: 10.1016/j.molmed.2024.04.010. Epub 2024 May 15. Trends Mol Med. 2024. PMID: 38755043 Review.

2

Sphingolipids in the Pathogenesis of Parkinson's Disease and Parkinsonism.

Lin G, Wang L, Marcogliese PC, Bellen HJ. Lin G, et al. Trends Endocrinol Metab. 2019 Feb;30(2):106-117. doi: 10.1016/j.tem.2018.11.003. Epub 2018 Dec 6. Trends Endocrinol Metab. 2019. PMID: 30528460 Review.

3

Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals.

Chen K, Ho TS, Lin G, Tan KL, Rasband MN, Bellen HJ. Chen K, et al. Among authors: lin g. Elife. 2016 Nov 30;5:e20732. doi: 10.7554/eLife.20732. Elife. 2016. PMID: 27901468 Free PMC article.

4

Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia.

Wang L, Lin G, Zuo Z, Li Y, Byeon SK, Pandey A, Bellen HJ. Wang L, et al. Among authors: lin g. Sci Adv. 2022 Jul 15;8(28):eabn3326. doi: 10.1126/sciadv.abn3326. Epub 2022 Jul 13. Sci Adv. 2022. PMID: 35857503 Free PMC article.

5

Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration.

Chen K, Lin G, Haelterman NA, Ho TS, Li T, Li Z, Duraine L, Graham BH, Jaiswal M, Yamamoto S, Rasband MN, Bellen HJ. Chen K, et al. Among authors: lin g. Elife. 2016 Jun 25;5:e16043. doi: 10.7554/eLife.16043. Elife. 2016. PMID: 27343351 Free PMC article.

6

Amyotrophic Lateral Sclerosis Pathogenesis Converges on Defects in Protein Homeostasis Associated with TDP-43 Mislocalization and Proteasome-Mediated Degradation Overload.

Lin G, Mao D, Bellen HJ. Lin G, et al. Curr Top Dev Biol. 2017;121:111-171. doi: 10.1016/bs.ctdb.2016.07.004. Epub 2016 Aug 13. Curr Top Dev Biol. 2017. PMID: 28057298 Review.

7

A kinase-dependent feedforward loop affects CREBB stability and long term memory formation.

Lee PT, Lin G, Lin WW, Diao F, White BH, Bellen HJ. Lee PT, et al. Among authors: lin ww, lin g. Elife. 2018 Feb 23;7:e33007. doi: 10.7554/eLife.33007. Elife. 2018. PMID: 29473541 Free PMC article.

8

Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain.

Lin G, Lee PT, Chen K, Mao D, Tan KL, Zuo Z, Lin WW, Wang L, Bellen HJ. Lin G, et al. Among authors: lin ww. Cell Metab. 2018 Oct 2;28(4):605-618.e6. doi: 10.1016/j.cmet.2018.05.019. Epub 2018 Jun 14. Cell Metab. 2018. PMID: 29909971 Free article.

9

Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification.

Şentürk M, Lin G, Zuo Z, Mao D, Watson E, Mikos AG, Bellen HJ. Şentürk M, et al. Among authors: lin g. Nat Cell Biol. 2019 Mar;21(3):384-396. doi: 10.1038/s41556-019-0281-x. Epub 2019 Feb 25. Nat Cell Biol. 2019. PMID: 30804504 Free PMC article.

10

Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14).

Lin G, Tepe B, McGrane G, Tipon RC, Croft G, Panwala L, Hope A, Liang AJH, Zuo Z, Byeon SK, Wang L, Pandey A, Bellen HJ. Lin G, et al. Elife. 2023 Jan 16;12:e82555. doi: 10.7554/eLife.82555. Elife. 2023. PMID: 36645408 Free PMC article.

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