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Dysregulation of TIM-3-galectin-9 pathway in the cystic fibrosis airways.
Vega-Carrascal I, Reeves EP, Niki T, Arikawa T, McNally P, O'Neill SJ, Hirashima M, McElvaney NG. Vega-Carrascal I, et al. Among authors: mcelvaney ng. J Immunol. 2011 Mar 1;186(5):2897-909. doi: 10.4049/jimmunol.1003187. Epub 2011 Jan 24. J Immunol. 2011. PMID: 21263071
Galectin-9 signaling through TIM-3 is involved in neutrophil-mediated Gram-negative bacterial killing: an effect abrogated within the cystic fibrosis lung.
Vega-Carrascal I, Bergin DA, McElvaney OJ, McCarthy C, Banville N, Pohl K, Hirashima M, Kuchroo VK, Reeves EP, McElvaney NG. Vega-Carrascal I, et al. Among authors: mcelvaney oj, mcelvaney ng. J Immunol. 2014 Mar 1;192(5):2418-31. doi: 10.4049/jimmunol.1300711. Epub 2014 Jan 29. J Immunol. 2014. PMID: 24477913 Free PMC article. Clinical Trial.
The Role of Neutrophils in Alpha-1 Antitrypsin Deficiency.
McCarthy C, Reeves EP, McElvaney NG. McCarthy C, et al. Among authors: mcelvaney ng. Ann Am Thorac Soc. 2016 Aug;13 Suppl 4:S297-304. doi: 10.1513/AnnalsATS.201509-634KV. Ann Am Thorac Soc. 2016. PMID: 27564664 Review.
Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity.
Reeves EP, Dunlea DM, McQuillan K, O'Dwyer CA, Carroll TP, Saldova R, Akepati PR, Wormald MR, McElvaney OJ, Shutchaidat V, Henry M, Meleady P, Keenan J, Liberti DC, Kotton DN, Rudd PM, Wilson AA, McElvaney NG. Reeves EP, et al. Among authors: mcelvaney oj, mcelvaney ng. J Immunol. 2019 Apr 15;202(8):2240-2253. doi: 10.4049/jimmunol.1801045. Epub 2019 Feb 22. J Immunol. 2019. PMID: 30796179 Free PMC article. Clinical Trial.
Anti-cytokines as a Strategy in Alpha-1 Antitrypsin Deficiency.
McElvaney OF, Murphy MP, Reeves EP, McElvaney NG. McElvaney OF, et al. Among authors: mcelvaney ng. Chronic Obstr Pulm Dis. 2020 Jul;7(3):203-213. doi: 10.15326/jcopdf.7.3.2019.0171. Chronic Obstr Pulm Dis. 2020. PMID: 32503090 Free PMC article. Review.
314 results