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Page 1
The impact of multi-omics in medicine.
Wang L, Qu J, Harari O, Boddey JA, Wang Z, Linna-Kuosmanen S. Wang L, et al. Among authors: linna kuosmanen s. Cell Rep Med. 2024 Sep 17;5(9):101742. doi: 10.1016/j.xcrm.2024.101742. Cell Rep Med. 2024. PMID: 39293398 Free PMC article. No abstract available.
Targeting IL-1 controls refractory pityriasis rubra pilaris.
Schmauch E, Severin Y, Xing X, Mangold A, Conrad C, Johannsen P, Kahlenberg JM, Mellett M, Navarini A, Nobbe S, Sarkar MK, Satyam A, Tsoi LC, French LE, Nilsson J, Linna-Kuosmanen S, Kaikkonen MU, Snijder B, Kellis M, Gudjonsson JE, Tsokos GC, Contassot E, Kolios AGA. Schmauch E, et al. Among authors: linna kuosmanen s. Sci Adv. 2024 Jul 5;10(27):eado2365. doi: 10.1126/sciadv.ado2365. Epub 2024 Jul 3. Sci Adv. 2024. PMID: 38959302 Free PMC article.
Transcriptomic and spatial dissection of human ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease.
Linna-Kuosmanen S, Schmauch E, Galani K, Ojanen J, Boix CA, Örd T, Toropainen A, Singha PK, Moreau PR, Harju K, Blazeski A, Segerstolpe Å, Lahtinen V, Hou L, Kang K, Meibalan E, Agudelo LZ, Kokki H, Halonen J, Jalkanen J, Gunn J, MacRae CA, Hollmén M, Hartikainen JEK, Kaikkonen MU, García-Cardeña G, Tavi P, Kiviniemi T, Kellis M. Linna-Kuosmanen S, et al. Cell Rep Med. 2024 May 21;5(5):101556. doi: 10.1016/j.xcrm.2024.101556. Cell Rep Med. 2024. PMID: 38776872 Free PMC article.
Integrative multi-omics profiling in human decedents receiving pig heart xenografts.
Schmauch E, Piening B, Mohebnasab M, Xia B, Zhu C, Stern J, Zhang W, Dowdell AK, Kim JI, Andrijevic D, Khalil K, Jaffe IS, Loza BL, Gragert L, Camellato BR, Oliveira MF, O'Brien DP, Chen HM, Weldon E, Gao H, Gandla D, Chang A, Bhatt R, Gao S, Lin X, Reddy KP, Kagermazova L, Habara AH, Widawsky S, Liang FX, Sall J, Loupy A, Heguy A, Taylor SEB, Zhu Y, Michael B, Jiang L, Jian R, Chong AS, Fairchild RL, Linna-Kuosmanen S, Kaikkonen MU, Tatapudi V, Lorber M, Ayares D, Mangiola M, Narula N, Moazami N, Pass H, Herati RS, Griesemer A, Kellis M, Snyder MP, Montgomery RA, Boeke JD, Keating BJ. Schmauch E, et al. Among authors: linna kuosmanen s. Nat Med. 2024 May;30(5):1448-1460. doi: 10.1038/s41591-024-02972-1. Epub 2024 May 17. Nat Med. 2024. PMID: 38760586
Global MicroRNA Profiling of Vascular Endothelial Cells.
Schmauch E, Levonen AL, Linna-Kuosmanen S. Schmauch E, et al. Among authors: linna kuosmanen s. Methods Mol Biol. 2022;2475:157-186. doi: 10.1007/978-1-0716-2217-9_11. Methods Mol Biol. 2022. PMID: 35451756
Profiling of Primary and Mature miRNA Expression in Atherosclerosis-Associated Cell Types.
Moreau PR, Tomas Bosch V, Bouvy-Liivrand M, Õunap K, Örd T, Pulkkinen HH, Pölönen P, Heinäniemi M, Ylä-Herttuala S, Laakkonen JP, Linna-Kuosmanen S, Kaikkonen MU. Moreau PR, et al. Among authors: linna kuosmanen s. Arterioscler Thromb Vasc Biol. 2021 Jul;41(7):2149-2167. doi: 10.1161/ATVBAHA.121.315579. Epub 2021 May 13. Arterioscler Thromb Vasc Biol. 2021. PMID: 33980036 Free PMC article.
NRF2 is a key regulator of endothelial microRNA expression under proatherogenic stimuli.
Linna-Kuosmanen S, Tomas Bosch V, Moreau PR, Bouvy-Liivrand M, Niskanen H, Kansanen E, Kivelä A, Hartikainen J, Hippeläinen M, Kokki H, Tavi P, Levonen AL, Kaikkonen MU. Linna-Kuosmanen S, et al. Cardiovasc Res. 2021 Apr 23;117(5):1339-1357. doi: 10.1093/cvr/cvaa219. Cardiovasc Res. 2021. PMID: 32683448 Free PMC article.