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Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry.
Ellis MJ, Lekka C, Holden KL, Tulmin H, Seedat F, O'Brien DP, Dhayal S, Zeissler ML, Knudsen JG, Kessler BM, Morgan NG, Todd JA, Richardson SJ, Stefana MI. Ellis MJ, et al. Among authors: o brien dp. Acta Neuropathol. 2024 May 18;147(1):87. doi: 10.1007/s00401-024-02729-7. Acta Neuropathol. 2024. PMID: 38761203 Free PMC article.
Tau depletion in human neurons mitigates Aβ-driven toxicity.
Ng B, Vowles J, Bertherat F, Abey A, Kilfeather P, Beccano-Kelly D, Stefana MI, O'Brien DP, Bengoa-Vergniory N, Carling PJ, Todd JA, Caffrey TM, Connor-Robson N, Cowley SA, Wade-Martins R. Ng B, et al. Mol Psychiatry. 2024 Jul;29(7):2009-2020. doi: 10.1038/s41380-024-02463-2. Epub 2024 Feb 15. Mol Psychiatry. 2024. PMID: 38361127 Free PMC article.
Deubiquitinases in muscle physiology and disorders.
Olie CS, O'Brien DP, Jones HBL, Liang Z, Damianou A, Sur-Erdem I, Pinto-Fernández A, Raz V, Kessler BM. Olie CS, et al. Among authors: o brien dp. Biochem Soc Trans. 2024 Jun 26;52(3):1085-1098. doi: 10.1042/BST20230562. Biochem Soc Trans. 2024. PMID: 38716888 Free PMC article. Review.
Quantitative proteomics reveals CLR interactome in primary human cells.
Manolis D, Hasan S, Maraveyas A, O'Brien DP, Kessler BM, Kramer H, Nikitenko LL. Manolis D, et al. Among authors: o brien dp. J Biol Chem. 2024 Jun;300(6):107399. doi: 10.1016/j.jbc.2024.107399. Epub 2024 May 20. J Biol Chem. 2024. PMID: 38777147 Free PMC article.
Deep Proteomics Network and Machine Learning Analysis of Human Cerebrospinal Fluid in Japanese Encephalitis Virus Infection.
Bharucha T, Gangadharan B, Kumar A, Myall AC, Ayhan N, Pastorino B, Chanthongthip A, Vongsouvath M, Mayxay M, Sengvilaipaseuth O, Phonemixay O, Rattanavong S, O'Brien DP, Vendrell I, Fischer R, Kessler B, Turtle L, de Lamballerie X, Dubot-Pérès A, Newton PN, Zitzmann N, SEAe Consortium. Bharucha T, et al. J Proteome Res. 2023 Jun 2;22(6):1614-1629. doi: 10.1021/acs.jproteome.2c00563. Epub 2023 May 23. J Proteome Res. 2023. PMID: 37219084 Free PMC article.
USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.
Gan J, Pinto-Fernández A, Flierman D, Akkermans JJLL, O'Brien DP, Greenwood H, Scott HC, Fritz G, Knobeloch KP, Neefjes J, van Dam H, Ovaa H, Ploegh HL, Kessler BM, Geurink PP, Sapmaz A. Gan J, et al. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2315163120. doi: 10.1073/pnas.2315163120. Epub 2023 Dec 6. Proc Natl Acad Sci U S A. 2023. PMID: 38055744 Free PMC article.
378 results