Leuzzi G - Search Results

1

Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens.

Walsh ZH, Shah P, Kothapalli N, Shah SB, Nikolenyi G, Brodtman DZ, Leuzzi G, Rogava M, Mu M, Ho P, Abuzaid S, Vasan N, AlQuraishi M, Milner JD, Ciccia A, Melms JC, Izar B. Walsh ZH, et al. Among authors: leuzzi g. Nat Biotechnol. 2024 May 23. doi: 10.1038/s41587-024-02235-x. Online ahead of print. Nat Biotechnol. 2024. PMID: 38783148

2

Crosstalk between mismatch repair and base excision repair in human gastric cancer.

Simonelli V, Leuzzi G, Basile G, D'Errico M, Fortini P, Franchitto A, Viti V, Brown AR, Parlanti E, Pascucci B, Palli D, Giuliani A, Palombo F, Sobol RW, Dogliotti E. Simonelli V, et al. Among authors: leuzzi g. Oncotarget. 2016 Jun 20;8(49):84827-84840. doi: 10.18632/oncotarget.10185. eCollection 2017 Oct 17. Oncotarget. 2016. PMID: 29156686 Free PMC article.

3

WRNIP1: A new guardian of genome integrity at stalled replication forks.

Leuzzi G, Marabitti V, Pichierri P, Franchitto A. Leuzzi G, et al. Mol Cell Oncol. 2016 Aug 3;3(5):e1215777. doi: 10.1080/23723556.2016.1215777. eCollection 2016. Mol Cell Oncol. 2016. PMID: 27857978 Free PMC article.

4

Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers.

Taglialatela A, Alvarez S, Leuzzi G, Sannino V, Ranjha L, Huang JW, Madubata C, Anand R, Levy B, Rabadan R, Cejka P, Costanzo V, Ciccia A. Taglialatela A, et al. Among authors: leuzzi g. Mol Cell. 2017 Oct 19;68(2):414-430.e8. doi: 10.1016/j.molcel.2017.09.036. Mol Cell. 2017. PMID: 29053959 Free PMC article.

5

The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection.

Billing D, Horiguchi M, Wu-Baer F, Taglialatela A, Leuzzi G, Nanez SA, Jiang W, Zha S, Szabolcs M, Lin CS, Ciccia A, Baer R. Billing D, et al. Among authors: leuzzi g. Mol Cell. 2018 Oct 4;72(1):127-139.e8. doi: 10.1016/j.molcel.2018.08.016. Epub 2018 Sep 20. Mol Cell. 2018. PMID: 30244837 Free PMC article.

6

Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant.

Nambiar TS, Billon P, Diedenhofen G, Hayward SB, Taglialatela A, Cai K, Huang JW, Leuzzi G, Cuella-Martin R, Palacios A, Gupta A, Egli D, Ciccia A. Nambiar TS, et al. Among authors: leuzzi g. Nat Commun. 2019 Jul 30;10(1):3395. doi: 10.1038/s41467-019-11105-z. Nat Commun. 2019. PMID: 31363085 Free PMC article.

7

MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage.

Huang JW, Acharya A, Taglialatela A, Nambiar TS, Cuella-Martin R, Leuzzi G, Hayward SB, Joseph SA, Brunette GJ, Anand R, Soni RK, Clark NL, Bernstein KA, Cejka P, Ciccia A. Huang JW, et al. Among authors: leuzzi g. Nat Commun. 2020 Jun 11;11(1):2948. doi: 10.1038/s41467-020-16718-3. Nat Commun. 2020. PMID: 32528060 Free PMC article.

8

Time for remodeling: SNF2-family DNA translocases in replication fork metabolism and human disease.

Joseph SA, Taglialatela A, Leuzzi G, Huang JW, Cuella-Martin R, Ciccia A. Joseph SA, et al. Among authors: leuzzi g. DNA Repair (Amst). 2020 Nov;95:102943. doi: 10.1016/j.dnarep.2020.102943. Epub 2020 Aug 15. DNA Repair (Amst). 2020. PMID: 32971328 Free PMC article. Review.

9

HATtracting Nucleases to Stalled Forks.

Leuzzi G, Taglialatela A, Ciccia A. Leuzzi G, et al. Mol Cell. 2020 Oct 15;80(2):177-180. doi: 10.1016/j.molcel.2020.09.031. Mol Cell. 2020. PMID: 33065018 Free article.

10

Functional interrogation of DNA damage response variants with base editing screens.

Cuella-Martin R, Hayward SB, Fan X, Chen X, Huang JW, Taglialatela A, Leuzzi G, Zhao J, Rabadan R, Lu C, Shen Y, Ciccia A. Cuella-Martin R, et al. Among authors: leuzzi g. Cell. 2021 Feb 18;184(4):1081-1097.e19. doi: 10.1016/j.cell.2021.01.041. Cell. 2021. PMID: 33606978 Free PMC article.

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