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Page 1
Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
Zálešák F, Nai F, Herok M, Bochenkova E, Bedi RK, Li Y, Errani F, Caflisch A. Zálešák F, et al. J Med Chem. 2024 Jun 13;67(11):9516-9535. doi: 10.1021/acs.jmedchem.4c00599. Epub 2024 May 24. J Med Chem. 2024. PMID: 38787793 Free PMC article.
Proteolysis Targeting Chimera Degraders of the METTL3-14 m6A-RNA Methyltransferase.
Errani F, Invernizzi A, Herok M, Bochenkova E, Stamm F, Corbeski I, Romanucci V, Di Fabio G, Zálešák F, Caflisch A. Errani F, et al. Among authors: zalesak f. JACS Au. 2024 Feb 12;4(2):713-729. doi: 10.1021/jacsau.4c00040. eCollection 2024 Feb 26. JACS Au. 2024. PMID: 38425900 Free PMC article.
Fragment Ligands of the m6A-RNA Reader YTHDF2.
Nai F, Nachawati R, Zálešák F, Wang X, Li Y, Caflisch A. Nai F, et al. Among authors: zalesak f. ACS Med Chem Lett. 2022 Aug 17;13(9):1500-1509. doi: 10.1021/acsmedchemlett.2c00303. eCollection 2022 Sep 8. ACS Med Chem Lett. 2022. PMID: 36110386 Free PMC article.
Heteroaryl sulfonamide synthesis: scope and limitations.
Iakovenko RO, Chrenko D, Kristek J, Desmedt E, Zálešák F, De Vleeschouwer F, Pospíšil J. Iakovenko RO, et al. Among authors: zalesak f. Org Biomol Chem. 2022 Apr 13;20(15):3154-3159. doi: 10.1039/d2ob00345g. Org Biomol Chem. 2022. PMID: 35343994
Unified Approach to Benzo[d]thiazol-2-yl-Sulfonamides.
Zálešák F, Kováč O, Lachetová E, Št'astná N, Pospíšil J. Zálešák F, et al. J Org Chem. 2021 Sep 3;86(17):11291-11309. doi: 10.1021/acs.joc.1c00317. Epub 2021 Aug 16. J Org Chem. 2021. PMID: 34479409