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Page 1
Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines.
Kocher D, Cao L, Guiho R, Langhammer M, Lai YL, Becker P, Hamdi H, Friedel D, Selt F, Vonhören D, Zaman J, Valinciute G, Herter S, Picard D, Rettenmeier J, Maass KK, Pajtler KW, Remke M, von Deimling A, Pusch S, Pfister SM, Oehme I, Jones DTW, Halbach S, Brummer T, Martinez-Barbera JP, Witt O, Milde T, Sigaud R. Kocher D, et al. Among authors: sigaud r. J Neurooncol. 2024 Jun;168(2):317-332. doi: 10.1007/s11060-024-04672-9. Epub 2024 Apr 17. J Neurooncol. 2024. PMID: 38630384 Free PMC article.
Generation of patient-derived pediatric pilocytic astrocytoma in-vitro models using SV40 large T: evaluation of a modeling workflow.
Selt F, El Damaty A, Schuhmann MU, Sigaud R, Ecker J, Sievers P, Kocher D, Herold-Mende C, Oehme I, von Deimling A, Pfister SM, Sahm F, Jones DTW, Witt O, Milde T. Selt F, et al. Among authors: sigaud r. J Neurooncol. 2023 Dec;165(3):467-478. doi: 10.1007/s11060-023-04500-6. Epub 2023 Nov 24. J Neurooncol. 2023. PMID: 37999877 Free PMC article.
Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma.
Picard D, Felsberg J, Langini M, Stachura P, Qin N, Macas J, Reiss Y, Bartl J, Selt F, Sigaud R, Meyer FD, Stefanski A, Stühler K, Roque L, Roque R, Pandyra AA, Brozou T, Knobbe-Thomsen C, Plate KH, Roesch A, Milde T, Reifenberger G, Leprivier G, Faria CC, Remke M. Picard D, et al. Among authors: sigaud r. Acta Neuropathol. 2023 Oct;146(4):551-564. doi: 10.1007/s00401-023-02626-5. Epub 2023 Sep 1. Acta Neuropathol. 2023. PMID: 37656187 Free PMC article.
MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas.
Sigaud R, Albert TK, Hess C, Hielscher T, Winkler N, Kocher D, Walter C, Münter D, Selt F, Usta D, Ecker J, Brentrup A, Hasselblatt M, Thomas C, Varghese J, Capper D, Thomale UW, Hernáiz Driever P, Simon M, Horn S, Herz NA, Koch A, Sahm F, Hamelmann S, Faria-Andrade A, Jabado N, Schuhmann MU, Schouten-van Meeteren AYN, Hoving E, Brummer T, van Tilburg CM, Pfister SM, Witt O, Jones DTW, Kerl K, Milde T. Sigaud R, et al. Nat Commun. 2023 Jul 27;14(1):4533. doi: 10.1038/s41467-023-40235-8. Nat Commun. 2023. PMID: 37500667 Free PMC article.
Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.
Valinciute G, Ecker J, Selt F, Hielscher T, Sigaud R, Ridinger J, Thatikonda V, Gatzweiler C, Robinson S, Talbot J, Bernardi F, Picard D, Blattner-Johnson M, Schmid S, Jones DT, van Tilburg CM, Capper D, Kool M, Remke M, Oehme I, Pfister SM, Roussel MF, Ayrault O, Witt O, Milde T. Valinciute G, et al. Among authors: sigaud r. J Neurooncol. 2023 May;163(1):143-158. doi: 10.1007/s11060-023-04319-1. Epub 2023 May 15. J Neurooncol. 2023. PMID: 37183219 Free PMC article.
Corrigendum to 'Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry' [Eur J Cancer 180 (2023) 71-84].
Ecker J, Selt F, Sturm D, Sill M, Korshunov A, Hirsch S, Capper D, Dikow N, Sutter C, Müller C, Sigaud R, Eggert A, Simon T, Niehues T, von Deimling A, Pajtler KW, van Tilburg CM, Jones DTW, Sahm F, Pfister SM, Witt O, Milde T. Ecker J, et al. Among authors: sigaud r. Eur J Cancer. 2023 May;184:200-201. doi: 10.1016/j.ejca.2023.02.024. Epub 2023 Mar 21. Eur J Cancer. 2023. PMID: 36959034 No abstract available.
Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry.
Ecker J, Selt F, Sturm D, Sill M, Korshunov A, Hirsch S, Capper D, Dikow N, Sutter C, Müller C, Sigaud R, Eggert A, Simon T, Niehues T, von Deimling A, Pajtler KW, van Tilburg CM, Jones DTW, Sahm F, Pfister SM, Witt O, Milde T. Ecker J, et al. Among authors: sigaud r. Eur J Cancer. 2023 Feb;180:71-84. doi: 10.1016/j.ejca.2022.11.015. Epub 2022 Nov 25. Eur J Cancer. 2023. PMID: 36542877
16 results