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Page 1
Targeting LxCxE cleft pocket of retinoblastoma protein in M2 macrophages inhibits ovarian cancer progression.
Tcyganov EN, Kwak T, Yang X, Poli ANR, Hart C, Bhuniya A, Cassel J, Kossenkov A, Auslander N, Lu L, Sharma P, Mendoza MGC, Zhigarev D, Cadungog MG, Jean S, Chatterjee-Paer S, Weiner D, Donthireddy L, Bristow B, Zhang R, Tyurin VA, Tyurina YY, Bayir H, Kagan VE, Salvino JM, Montaner LJ. Tcyganov EN, et al. Among authors: poli anr. bioRxiv [Preprint]. 2024 May 14:2024.05.10.593562. doi: 10.1101/2024.05.10.593562. bioRxiv. 2024. PMID: 38798466 Free PMC article. Preprint.
A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors.
Barnoud T, Leung JC, Leu JI, Basu S, Poli ANR, Parris JLD, Indeglia A, Martynyuk T, Good M, Gnanapradeepan K, Sanseviero E, Moeller R, Tang HY, Cassel J, Kossenkov AV, Liu Q, Speicher DW, Gabrilovich DI, Salvino JM, George DL, Murphy ME. Barnoud T, et al. Among authors: poli anr. Cancer Res. 2020 Dec 1;80(23):5270-5281. doi: 10.1158/0008-5472.CAN-20-0397. Epub 2020 Oct 6. Cancer Res. 2020. PMID: 33023943 Free PMC article.
5-chloro-3-(2-(2,4-dinitrophenyl) hydrazono)indolin-2-one: synthesis, characterization, biochemical and computational screening against SARS-CoV-2.
Majoumo-Mbe F, Sangbong NA, Tadjong Tcho A, Namba-Nzanguim CT, Simoben CV, Eni DB, Alhaji Isa M, Poli ANR, Cassel J, Salvino JM, Montaner LJ, Tietjen I, Ntie-Kang F. Majoumo-Mbe F, et al. Among authors: poli anr. Chem Zvesti. 2024;78(6):3431-3441. doi: 10.1007/s11696-023-03274-5. Epub 2024 Mar 14. Chem Zvesti. 2024. PMID: 38685970 Free PMC article.
HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer.
Ferretti GDS, Quaas CE, Bertolini I, Zuccotti A, Saatci O, Kashatus JA, Sharmin S, Lu DY, Poli ANR, Quesnelle AF, Rodriguez-Blanco J, de Cubas AA, Hobbs GA, Liu Q, O'Bryan JP, Salvino JM, Kashatus DF, Sahin O, Barnoud T. Ferretti GDS, et al. Among authors: poli anr. Cell Death Differ. 2024 Jul;31(7):881-896. doi: 10.1038/s41418-024-01310-9. Epub 2024 May 28. Cell Death Differ. 2024. PMID: 38802657 Free PMC article.
Design of novel and highly selective SARS-CoV-2 main protease inhibitors.
Poli ANR, Tietjen I, Nandwana NK, Cassel J, Messick TE, Register ET, Keeney F, Rajaiah R, Verma AK, Pandey K, Acharya A, Byrareddy SN, Montaner LJ, Salvino JM. Poli ANR, et al. Antimicrob Agents Chemother. 2024 Oct 8;68(10):e0056224. doi: 10.1128/aac.00562-24. Epub 2024 Sep 3. Antimicrob Agents Chemother. 2024. PMID: 39225484 Free PMC article.
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