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Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS-CoV-2 Main Protease with Antiviral Activity.
Harrison K, Carlos PW, Ullrich S, Aggarwal A, Johansen-Leete J, Sasi VM, Barter I, Maxwell JWC, Bedding MJ, Larance M, Turville S, Norman A, Jackson CJ, Nitsche C, Payne RJ. Harrison K, et al. Among authors: maxwell jwc. Chemistry. 2024 Aug 6;30(44):e202401606. doi: 10.1002/chem.202401606. Epub 2024 Jul 17. Chemistry. 2024. PMID: 38801240
Expressed Protein Selenoester Ligation.
Kulkarni SS, Watson EE, Maxwell JWC, Niederacher G, Johansen-Leete J, Huhmann S, Mukherjee S, Norman AR, Kriegesmann J, Becker CFW, Payne RJ. Kulkarni SS, et al. Among authors: maxwell jwc. Angew Chem Int Ed Engl. 2022 May 9;61(20):e202200163. doi: 10.1002/anie.202200163. Epub 2022 Mar 9. Angew Chem Int Ed Engl. 2022. PMID: 35194928 Free PMC article.
Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice.
Ashhurst AS, Johansen MD, Maxwell JWC, Stockdale S, Ashley CL, Aggarwal A, Siddiquee R, Miemczyk S, Nguyen DH, Mackay JP, Counoupas C, Byrne SN, Turville S, Steain M, Triccas JA, Hansbro PM, Payne RJ, Britton WJ. Ashhurst AS, et al. Among authors: maxwell jwc. Nat Commun. 2022 Nov 15;13(1):6972. doi: 10.1038/s41467-022-34297-3. Nat Commun. 2022. PMID: 36379950 Free PMC article.
Synthesis and applications of mirror-image proteins.
Harrison K, Mackay AS, Kambanis L, Maxwell JWC, Payne RJ. Harrison K, et al. Among authors: maxwell jwc. Nat Rev Chem. 2023 Jun;7(6):383-404. doi: 10.1038/s41570-023-00493-y. Epub 2023 May 12. Nat Rev Chem. 2023. PMID: 37173596 Review.
Electrochemical Modification of Polypeptides at Selenocysteine.
Mackay AS, Maxwell JWC, Bedding MJ, Kulkarni SS, Byrne SA, Kambanis L, Popescu MV, Paton RS, Malins LR, Ashhurst AS, Corcilius L, Payne RJ. Mackay AS, et al. Among authors: maxwell jwc. Angew Chem Int Ed Engl. 2023 Dec 11;62(50):e202313037. doi: 10.1002/anie.202313037. Epub 2023 Nov 9. Angew Chem Int Ed Engl. 2023. PMID: 37818778
17 results