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Digital detection of endonuclease mediated gene disruption in the HIV provirus.
Sedlak RH, Liang S, Niyonzima N, De Silva Feelixge HS, Roychoudhury P, Greninger AL, Weber ND, Boissel S, Scharenberg AM, Cheng A, Magaret A, Bumgarner R, Stone D, Jerome KR. Sedlak RH, et al. Among authors: roychoudhury p. Sci Rep. 2016 Feb 2;6:20064. doi: 10.1038/srep20064. Sci Rep. 2016. PMID: 26829887 Free PMC article.
In vivo disruption of latent HSV by designer endonuclease therapy.
Aubert M, Madden EA, Loprieno M, DeSilva Feelixge HS, Stensland L, Huang ML, Greninger AL, Roychoudhury P, Niyonzima N, Nguyen T, Magaret A, Galleto R, Stone D, Jerome KR. Aubert M, et al. Among authors: roychoudhury p. JCI Insight. 2016 Sep 8;1(14):e88468. doi: 10.1172/jci.insight.88468. JCI Insight. 2016. PMID: 27642635 Free PMC article.
Highly conserved intragenic HSV-2 sequences: Results from next-generation sequencing of HSV-2 UL and US regions from genital swabs collected from 3 continents.
Johnston C, Magaret A, Roychoudhury P, Greninger AL, Cheng A, Diem K, Fitzgibbon MP, Huang ML, Selke S, Lingappa JR, Celum C, Jerome KR, Wald A, Koelle DM. Johnston C, et al. Among authors: roychoudhury p. Virology. 2017 Oct;510:90-98. doi: 10.1016/j.virol.2017.06.031. Epub 2017 Jul 13. Virology. 2017. PMID: 28711653 Free PMC article.
Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses.
Niyonzima N, Lambert AR, Werther R, De Silva Feelixge H, Roychoudhury P, Greninger AL, Stone D, Stoddard BL, Jerome KR. Niyonzima N, et al. Among authors: roychoudhury p. Protein Eng Des Sel. 2017 Jul 1;30(7):503-522. doi: 10.1093/protein/gzx037. Protein Eng Des Sel. 2017. PMID: 28873986 Free PMC article.
Dual-strain genital herpes simplex virus type 2 (HSV-2) infection in the US, Peru, and 8 countries in sub-Saharan Africa: A nested cross-sectional viral genotyping study.
Johnston C, Magaret A, Roychoudhury P, Greninger AL, Reeves D, Schiffer J, Jerome KR, Sather C, Diem K, Lingappa JR, Celum C, Koelle DM, Wald A. Johnston C, et al. Among authors: roychoudhury p. PLoS Med. 2017 Dec 27;14(12):e1002475. doi: 10.1371/journal.pmed.1002475. eCollection 2017 Dec. PLoS Med. 2017. PMID: 29281620 Free PMC article.
Copy Number Heterogeneity, Large Origin Tandem Repeats, and Interspecies Recombination in Human Herpesvirus 6A (HHV-6A) and HHV-6B Reference Strains.
Greninger AL, Roychoudhury P, Makhsous N, Hanson D, Chase J, Krueger G, Xie H, Huang ML, Saunders L, Ablashi D, Koelle DM, Cook L, Jerome KR. Greninger AL, et al. Among authors: roychoudhury p. J Virol. 2018 Apr 27;92(10):e00135-18. doi: 10.1128/JVI.00135-18. Print 2018 May 15. J Virol. 2018. PMID: 29491155 Free PMC article.
CRISPR/Cas9 and Genome Editing for Viral Disease-Is Resistance Futile?
De Silva Feelixge HS, Stone D, Roychoudhury P, Aubert M, Jerome KR. De Silva Feelixge HS, et al. Among authors: roychoudhury p. ACS Infect Dis. 2018 Jun 8;4(6):871-880. doi: 10.1021/acsinfecdis.7b00273. Epub 2018 Mar 21. ACS Infect Dis. 2018. PMID: 29522311 Free PMC article. Review.
Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6.
Greninger AL, Knudsen GM, Roychoudhury P, Hanson DJ, Sedlak RH, Xie H, Guan J, Nguyen T, Peddu V, Boeckh M, Huang ML, Cook L, Depledge DP, Zerr DM, Koelle DM, Gantt S, Yoshikawa T, Caserta M, Hill JA, Jerome KR. Greninger AL, et al. Among authors: roychoudhury p. BMC Genomics. 2018 Mar 20;19(1):204. doi: 10.1186/s12864-018-4604-2. BMC Genomics. 2018. PMID: 29554870 Free PMC article.
Ultrasensitive Capture of Human Herpes Simplex Virus Genomes Directly from Clinical Samples Reveals Extraordinarily Limited Evolution in Cell Culture.
Greninger AL, Roychoudhury P, Xie H, Casto A, Cent A, Pepper G, Koelle DM, Huang ML, Wald A, Johnston C, Jerome KR. Greninger AL, et al. Among authors: roychoudhury p. mSphere. 2018 Jun 13;3(3):e00283-18. doi: 10.1128/mSphereDirect.00283-18. Print 2018 Jun 27. mSphere. 2018. PMID: 29898986 Free PMC article.
230 results