Koivunen P - Search Results

1

Activation of the hypoxia-inducible factor pathway by roxadustat improves glucose metabolism in human primary myotubes from men.

Mäkinen S, Sree S, Ala-Nisula T, Kultalahti H, Koivunen P, Koistinen HA. Mäkinen S, et al. Among authors: koivunen p. Diabetologia. 2024 Sep;67(9):1943-1954. doi: 10.1007/s00125-024-06185-6. Epub 2024 May 30. Diabetologia. 2024. PMID: 38814443 Free PMC article.

2

Hypoxia-Inducible Factor Prolyl 4-Hydroxylases and Metabolism.

Koivunen P, Kietzmann T. Koivunen P, et al. Trends Mol Med. 2018 Dec;24(12):1021-1035. doi: 10.1016/j.molmed.2018.10.004. Epub 2018 Nov 1. Trends Mol Med. 2018. PMID: 30391126 Review.

3

Human phytanoyl-CoA dioxygenase domain-containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism.

Ala-Nisula T, Sah-Teli SK, Ronkainen VP, Dimova EY, Koivunen P. Ala-Nisula T, et al. Among authors: koivunen p. FEBS Lett. 2023 Jun;597(12):1651-1666. doi: 10.1002/1873-3468.14666. Epub 2023 Jun 1. FEBS Lett. 2023. PMID: 37235702 Free article.

4

Metabolic characteristics of transmembrane prolyl 4-hydroxylase (P4H-TM) deficient mice.

Ala-Nisula T, Halmetoja R, Leinonen H, Kurkela M, Lipponen HR, Sakko S, Karpale M, Salo AM, Sissala N, Röning T, Raza GS, Mäkelä KA, Thevenot J, Herzig KH, Serpi R, Myllyharju J, Tanila H, Koivunen P, Dimova EY. Ala-Nisula T, et al. Among authors: koivunen p. Pflugers Arch. 2024 Sep;476(9):1339-1351. doi: 10.1007/s00424-024-02920-5. Epub 2024 Feb 24. Pflugers Arch. 2024. PMID: 38396259 Free PMC article.

5

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor.

Hirsilä M, Koivunen P, Günzler V, Kivirikko KI, Myllyharju J. Hirsilä M, et al. Among authors: koivunen p. J Biol Chem. 2003 Aug 15;278(33):30772-80. doi: 10.1074/jbc.M304982200. Epub 2003 Jun 3. J Biol Chem. 2003. PMID: 12788921 Free article.

6

The length of peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases.

Koivunen P, Hirsilä M, Kivirikko KI, Myllyharju J. Koivunen P, et al. J Biol Chem. 2006 Sep 29;281(39):28712-20. doi: 10.1074/jbc.M604628200. Epub 2006 Aug 1. J Biol Chem. 2006. PMID: 16885164 Free article.

7

Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF.

Koivunen P, Hirsilä M, Remes AM, Hassinen IE, Kivirikko KI, Myllyharju J. Koivunen P, et al. J Biol Chem. 2007 Feb 16;282(7):4524-4532. doi: 10.1074/jbc.M610415200. Epub 2006 Dec 19. J Biol Chem. 2007. PMID: 17182618 Free article.

8

Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.

Hyvärinen J, Hassinen IE, Sormunen R, Mäki JM, Kivirikko KI, Koivunen P, Myllyharju J. Hyvärinen J, et al. Among authors: koivunen p. J Biol Chem. 2010 Apr 30;285(18):13646-57. doi: 10.1074/jbc.M109.084855. Epub 2010 Feb 25. J Biol Chem. 2010. PMID: 20185832 Free PMC article.

9

Hypoxia-inducible factor prolyl 4-hydroxylases: common and specific roles.

Myllyharju J, Koivunen P. Myllyharju J, et al. Among authors: koivunen p. Biol Chem. 2013 Apr;394(4):435-48. doi: 10.1515/hsz-2012-0328. Biol Chem. 2013. PMID: 23324380 Review.

10

Activation of hypoxia response in endothelial cells contributes to ischemic cardioprotection.

Kerkelä R, Karsikas S, Szabo Z, Serpi R, Magga J, Gao E, Alitalo K, Anisimov A, Sormunen R, Pietilä I, Vainio L, Koch WJ, Kivirikko KI, Myllyharju J, Koivunen P. Kerkelä R, et al. Among authors: koivunen p. Mol Cell Biol. 2013 Aug;33(16):3321-9. doi: 10.1128/MCB.00432-13. Epub 2013 Jun 17. Mol Cell Biol. 2013. PMID: 23775121 Free PMC article.

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