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SosA inhibits cell division in Staphylococcus aureus in response to DNA damage.
Bojer MS, Wacnik K, Kjelgaard P, Gallay C, Bottomley AL, Cohn MT, Lindahl G, Frees D, Veening JW, Foster SJ, Ingmer H. Bojer MS, et al. Among authors: veening jw. Mol Microbiol. 2019 Oct;112(4):1116-1130. doi: 10.1111/mmi.14350. Epub 2019 Aug 16. Mol Microbiol. 2019. PMID: 31290194 Free PMC article.
The ClpX chaperone controls autolytic splitting of Staphylococcus aureus daughter cells, but is bypassed by β-lactam antibiotics or inhibitors of WTA biosynthesis.
Jensen C, Bæk KT, Gallay C, Thalsø-Madsen I, Xu L, Jousselin A, Ruiz Torrubia F, Paulander W, Pereira AR, Veening JW, Pinho MG, Frees D. Jensen C, et al. Among authors: veening jw. PLoS Pathog. 2019 Sep 13;15(9):e1008044. doi: 10.1371/journal.ppat.1008044. eCollection 2019 Sep. PLoS Pathog. 2019. PMID: 31518377 Free PMC article.
CcrZ is a pneumococcal spatiotemporal cell cycle regulator that interacts with FtsZ and controls DNA replication by modulating the activity of DnaA.
Gallay C, Sanselicio S, Anderson ME, Soh YM, Liu X, Stamsås GA, Pelliciari S, van Raaphorst R, Dénéréaz J, Kjos M, Murray H, Gruber S, Grossman AD, Veening JW. Gallay C, et al. Among authors: veening jw. Nat Microbiol. 2021 Sep;6(9):1175-1187. doi: 10.1038/s41564-021-00949-1. Epub 2021 Aug 9. Nat Microbiol. 2021. PMID: 34373624 Free PMC article.
Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence.
Minhas V, Domenech A, Synefiaridou D, Straume D, Brendel M, Cebrero G, Liu X, Costa C, Baldry M, Sirard JC, Perez C, Gisch N, Hammerschmidt S, Håvarstein LS, Veening JW. Minhas V, et al. Among authors: veening jw. PLoS Biol. 2023 Jan 30;21(1):e3001990. doi: 10.1371/journal.pbio.3001990. eCollection 2023 Jan. PLoS Biol. 2023. PMID: 36716340 Free PMC article.
120 results