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A microglia-containing cerebral organoid model to study early life immune challenges.
Buonfiglioli A, Kübler R, Missall R, De Jong R, Chan S, Haage V, Wendt S, Lin AJ, Mattei D, Graziani M, Latour B, Gigase F, Nygaard HB, De Jager PL, De Witte LD. Buonfiglioli A, et al. Among authors: mattei d. bioRxiv [Preprint]. 2024 May 29:2024.05.24.595814. doi: 10.1101/2024.05.24.595814. bioRxiv. 2024. Update in: Brain Behav Immun. 2024 Nov 3;123:1127-1146. doi: 10.1016/j.bbi.2024.11.008. PMID: 38826204 Free PMC article. Updated. Preprint.
Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing.
Humphrey J, Brophy E, Kosoy R, Zeng B, Coccia E, Mattei D, Ravi A, Efthymiou AG, Navarro E, Muller BZ, Snijders GJ, Allan A, Münch A, Kitata RB, Kleopoulos SP, Argyriou S, Shao Z, Francoeur N, Tsai CF, Gritsenko MA, Monroe ME, Paurus VL, Weitz KK, Shi T, Sebra R, Liu T, de Witte LD, Goate AM, Bennett DA, Haroutunian V, Hoffman GE, Fullard JF, Roussos P, Raj T. Humphrey J, et al. Among authors: mattei d. medRxiv [Preprint]. 2023 Dec 1:2023.12.01.23299073. doi: 10.1101/2023.12.01.23299073. medRxiv. 2023. PMID: 38076956 Free PMC article. Preprint.
Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.
Mattei D, Ivanov A, Ferrai C, Jordan P, Guneykaya D, Buonfiglioli A, Schaafsma W, Przanowski P, Deuther-Conrad W, Brust P, Hesse S, Patt M, Sabri O, Ross TL, Eggen BJL, Boddeke EWGM, Kaminska B, Beule D, Pombo A, Kettenmann H, Wolf SA. Mattei D, et al. Transl Psychiatry. 2017 May 9;7(5):e1120. doi: 10.1038/tp.2017.80. Transl Psychiatry. 2017. PMID: 28485733 Free PMC article.
Adolescence is a sensitive period for prefrontal microglia to act on cognitive development.
Schalbetter SM, von Arx AS, Cruz-Ochoa N, Dawson K, Ivanov A, Mueller FS, Lin HY, Amport R, Mildenberger W, Mattei D, Beule D, Földy C, Greter M, Notter T, Meyer U. Schalbetter SM, et al. Among authors: mattei d. Sci Adv. 2022 Mar 4;8(9):eabi6672. doi: 10.1126/sciadv.abi6672. Epub 2022 Mar 2. Sci Adv. 2022. PMID: 35235358 Free PMC article.
A microglia-containing cerebral organoid model to study early life immune challenges.
Buonfiglioli A, Kübler R, Missall R, De Jong R, Chan S, Haage V, Wendt S, Lin AJ, Mattei D, Graziani M, Latour B, Gigase F, Chiu R, Zhang Y, Nygaard HB, De Jager PL, De Witte LD. Buonfiglioli A, et al. Among authors: mattei d. Brain Behav Immun. 2024 Nov 3;123:1127-1146. doi: 10.1016/j.bbi.2024.11.008. Online ahead of print. Brain Behav Immun. 2024. PMID: 39500415
TYROBP/DAP12 knockout in Huntington's disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration.
Creus-Muncunill J, Haure-Mirande JV, Mattei D, Bons J, Ramirez AV, Hamilton BW, Corwin C, Chowdhury S, Schilling B, Ellerby LM, Ehrlich ME. Creus-Muncunill J, et al. Among authors: mattei d. J Neuroinflammation. 2024 Mar 8;21(1):66. doi: 10.1186/s12974-024-03052-4. J Neuroinflammation. 2024. PMID: 38459557 Free PMC article.
Pegaspargase-modified risk-oriented program for adult acute lymphoblastic leukemia: results of the GIMEMA LAL1913 trial.
Bassan R, Chiaretti S, Della Starza I, Spinelli O, Santoro A, Paoloni F, Messina M, Elia L, De Propris MS, Scattolin AM, Audisio E, Marbello L, Borlenghi E, Zappasodi P, Mauro E, Martinelli G, Mattei D, Fracchiolla N, Bocchia M, De Fabritiis P, Bonifacio M, Candoni A, Cassibba V, Di Bartolomeo P, Latte G, Trappolini S, Guarini A, Vitale A, Fazi P, Piciocchi A, Rambaldi A, Foà R. Bassan R, et al. Among authors: mattei d. Blood Adv. 2023 Aug 22;7(16):4448-4461. doi: 10.1182/bloodadvances.2022009596. Blood Adv. 2023. PMID: 37276451 Free PMC article.
159 results