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Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel.
Zhang SM, Paulin CBJ, Shu H, Yagüe-Capilla M, Michel M, Marttila P, Ortis F, Bwanika HC, Dirks C, Venkatram RP, Wiita E, Jemth AS, Almlöf I, Loseva O, Hormann FM, Koolmeister T, Linde E, Lee S, Llona-Minguez S, Haraldsson M, Axelsson H, Strömberg K, Homan EJ, Scobie M, Lundbäck T, Helleday T, Rudd SG. Zhang SM, et al. Among authors: bwanika hc. iScience. 2024 Jan 13;27(2):108907. doi: 10.1016/j.isci.2024.108907. eCollection 2024 Feb 16. iScience. 2024. PMID: 38318365 Free PMC article.
The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients.
Åkerlund E, Gudoityte G, Moussaud-Lamodière E, Lind O, Bwanika HC, Lehti K, Salehi S, Carlson J, Wallin E, Fernebro J, Östling P, Kallioniemi O, Joneborg U, Seashore-Ludlow B. Åkerlund E, et al. Among authors: bwanika hc. NPJ Precis Oncol. 2023 Oct 31;7(1):111. doi: 10.1038/s41698-023-00463-z. NPJ Precis Oncol. 2023. PMID: 37907613 Free PMC article.