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Page 1
Neutral or Detrimental Effects of TREM2 Agonist Antibodies in Preclinical Models of Alzheimer's Disease and Multiple Sclerosis.
Etxeberria A, Shen YA, Vito S, Silverman SM, Imperio J, Lalehzadeh G, Soung AL, Du C, Xie L, Choy MK, Hsiao YC, Ngu H, Cho CH, Ghosh S, Novikova G, Rezzonico MG, Leahey R, Weber M, Gogineni A, Elstrott J, Xiong M, Greene JJ, Stark KL, Chan P, Roth GA, Adrian M, Li Q, Choi M, Wong WR, Sandoval W, Foreman O, Nugent AA, Friedman BA, Sadekar S, Hötzel I, Hansen DV, Chih B, Yuen TJ, Weimer RM, Easton A, Meilandt WJ, Bohlen CJ. Etxeberria A, et al. Among authors: rezzonico mg. J Neurosci. 2024 Jul 17;44(29):e2347232024. doi: 10.1523/JNEUROSCI.2347-23.2024. J Neurosci. 2024. PMID: 38830764
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology.
Lee SH, Meilandt WJ, Xie L, Gandham VD, Ngu H, Barck KH, Rezzonico MG, Imperio J, Lalehzadeh G, Huntley MA, Stark KL, Foreman O, Carano RAD, Friedman BA, Sheng M, Easton A, Bohlen CJ, Hansen DV. Lee SH, et al. Among authors: rezzonico mg. Neuron. 2021 Apr 21;109(8):1283-1301.e6. doi: 10.1016/j.neuron.2021.02.010. Epub 2021 Mar 5. Neuron. 2021. PMID: 33675684 Free article.
Disease-associated oligodendrocyte responses across neurodegenerative diseases.
Pandey S, Shen K, Lee SH, Shen YA, Wang Y, Otero-García M, Kotova N, Vito ST, Laufer BI, Newton DF, Rezzonico MG, Hanson JE, Kaminker JS, Bohlen CJ, Yuen TJ, Friedman BA. Pandey S, et al. Among authors: rezzonico mg. Cell Rep. 2022 Aug 23;40(8):111189. doi: 10.1016/j.celrep.2022.111189. Cell Rep. 2022. PMID: 36001972 Free article.
Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models.
Dejanovic B, Wu T, Tsai MC, Graykowski D, Gandham VD, Rose CM, Bakalarski CE, Ngu H, Wang Y, Pandey S, Rezzonico MG, Friedman BA, Edmonds R, De Mazière A, Rakosi-Schmidt R, Singh T, Klumperman J, Foreman O, Chang MC, Xie L, Sheng M, Hanson JE. Dejanovic B, et al. Among authors: rezzonico mg. Nat Aging. 2022 Sep;2(9):837-850. doi: 10.1038/s43587-022-00281-1. Epub 2022 Sep 20. Nat Aging. 2022. PMID: 37118504 Free PMC article.
Primate cerebrospinal fluid CHI3L1 reflects brain TREM2 agonism.
Schauer SP, Cho CH, Novikova G, Roth GA, Lee J, Sharma AD, Foley AR, Ng C, Shen P, Choi M, Ma TP, Phu L, Budayeva HG, Cheung TK, Lalehzadeh G, Imperio J, Ngu H, Etxeberria A, Liang Y, Rezzonico MG, Dourado M, Huang K, Lai Z, Hokom M, Pandya NJ, Newton D, Abdel-Haleem AM, Chan P, Lee D, Tassew NG, Sangaraju D, O'Connor D, Hötzel I, Stark KL, Chou C, Foreman O, Easton A, Wildsmith KR, Sperinde G, Rose CM, Friedman BA, Fuji RN, Weimer RM, Meilandt WJ, Sadekar S, Nugent AA, Biever A. Schauer SP, et al. Among authors: rezzonico mg. Alzheimers Dement. 2024 Sep;20(9):5861-5888. doi: 10.1002/alz.13921. Epub 2024 Aug 1. Alzheimers Dement. 2024. PMID: 39090679 Free PMC article.
Fully defined NGN2 neuron protocol reveals diverse signatures of neuronal maturation.
Shan X, Zhang A, Rezzonico MG, Tsai MC, Sanchez-Priego C, Zhang Y, Chen MB, Choi M, Andrade López JM, Phu L, Cramer AL, Zhang Q, Pattison JM, Rose CM, Hoogenraad CC, Jeong CG. Shan X, et al. Among authors: rezzonico mg. Cell Rep Methods. 2024 Sep 16;4(9):100858. doi: 10.1016/j.crmeth.2024.100858. Epub 2024 Sep 9. Cell Rep Methods. 2024. PMID: 39255791 Free PMC article.