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Multiomic profiling of transcription factor binding and function in human brain.
Loupe JM, Anderson AG, Rizzardi LF, Rodriguez-Nunez I, Moyers B, Trausch-Lowther K, Jain R, Bunney WE, Bunney BG, Cartagena P, Sequeira A, Watson SJ, Akil H, Cooper GM, Myers RM. Loupe JM, et al. Among authors: watson sj. Nat Neurosci. 2024 Jul;27(7):1387-1399. doi: 10.1038/s41593-024-01658-8. Epub 2024 Jun 3. Nat Neurosci. 2024. PMID: 38831039
Allele biased transcription factor binding across human brain regions gives mechanistic insight into eQTLs.
Moyers BA, Loupe JM, Felker SA, Lawlor JMJ, Anderson AG, Rodriguez-Nunez I, Bunney WE, Bunney BG, Cartagena PM, Sequeira A, Watson SJ, Akil H, Mendenhall EM, Cooper GM, Myers RM. Moyers BA, et al. Among authors: watson sj. bioRxiv [Preprint]. 2023 Oct 9:2023.10.06.561245. doi: 10.1101/2023.10.06.561245. bioRxiv. 2023. Update in: Genome Res. 2024 Sep 20;34(8):1224-1234. doi: 10.1101/gr.278601.123 PMID: 37873117 Free PMC article. Updated. Preprint.
Adolescent environmental enrichment induces social resilience and alters neural gene expression in a selectively bred rodent model with anxious phenotype.
O'Connor AM, Hagenauer MH, Thew Forrester LC, Maras PM, Arakawa K, Hebda-Bauer EK, Khalil H, Richardson ER, Rob FI, Sannah Y, Watson SJ Jr, Akil H. O'Connor AM, et al. Among authors: watson sj jr. Neurobiol Stress. 2024 May 30;31:100651. doi: 10.1016/j.ynstr.2024.100651. eCollection 2024 Jul. Neurobiol Stress. 2024. PMID: 38933284 Free PMC article.
Resource: A curated database of brain-related functional gene sets (Brain.GMT).
Hagenauer MH, Sannah Y, Hebda-Bauer EK, Rhoads C, O'Connor AM, Flandreau E, Watson SJ Jr, Akil H. Hagenauer MH, et al. Among authors: watson sj jr. MethodsX. 2024 Jun 24;13:102788. doi: 10.1016/j.mex.2024.102788. eCollection 2024 Dec. MethodsX. 2024. PMID: 39049932 Free PMC article.
A meta-analysis of the effects of early life stress on the prefrontal cortex transcriptome suggests long-term effects on myelin.
Duan TQ, Hagenauer MH, Flandreau EI, Bader A, Nguyen DM, Maras PM, Merscher S De Lima R, Gyles T, Mclain C, Meaney MJ, Nestler EJ, Watson SJ, Akil H. Duan TQ, et al. Among authors: watson sj. bioRxiv [Preprint]. 2024 Nov 24:2024.11.22.624315. doi: 10.1101/2024.11.22.624315. bioRxiv. 2024. PMID: 39605735 Free PMC article. Preprint.
The Tuberculosis Drug Candidate SQ109 and Its Analogs Have Multistage Activity against Plasmodium falciparum.
Watson SJ, van der Watt ME, Theron A, Reader J, Tshabalala S, Erlank E, Koekemoer LL, Naude M, Stampolaki M, Adewole F, Sadowska K, Pérez-Lozano P, Turcu AL, Vázquez S, Ko J, Mazurek B, Singh D, Malwal SR, Njoroge M, Chibale K, Onajole OK, Kolocouris A, Oldfield E, Birkholtz LM. Watson SJ, et al. ACS Infect Dis. 2024 Sep 13;10(9):3358-3367. doi: 10.1021/acsinfecdis.4c00461. Epub 2024 Aug 14. ACS Infect Dis. 2024. PMID: 39143042 Free PMC article.
640 results