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Comprehensive Target Engagement by the EZH2 Inhibitor Tulmimetostat Allows for Targeting of ARID1A Mutant Cancers.
Keller PJ, Adams EJ, Wu R, Côté A, Arora S, Cantone N, Meyer R, Mertz JA, Gehling V, Cui J, Stuckey JI, Khanna A, Zhao F, Chen Z, Yu Z, Cummings RT, Taimi M, Lakhani NJ, Rasco D, Gutierrez M, Duska L, Devitt M, Rippley R, Levell J, Truong J, Wang J, Sun K, Trojer P. Keller PJ, et al. Among authors: khanna a. Cancer Res. 2024 Aug 1;84(15):2501-2517. doi: 10.1158/0008-5472.CAN-24-0398. Cancer Res. 2024. PMID: 38833522 Free PMC article. Clinical Trial.
Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time.
Khanna A, Côté A, Arora S, Moine L, Gehling VS, Brenneman J, Cantone N, Stuckey JI, Apte S, Ramakrishnan A, Bruderek K, Bradley WD, Audia JE, Cummings RT, Sims RJ 3rd, Trojer P, Levell JR. Khanna A, et al. ACS Med Chem Lett. 2020 Mar 26;11(6):1205-1212. doi: 10.1021/acsmedchemlett.0c00045. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32551002 Free PMC article.
Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activity.
Stuckey JI, Cantone NR, Côté A, Arora S, Vivat V, Ramakrishnan A, Mertz JA, Khanna A, Brenneman J, Gehling VS, Moine L, Sims RJ 3rd, Audia JE, Trojer P, Levell JR, Cummings RT. Stuckey JI, et al. Among authors: khanna a. J Biol Chem. 2021 Jan-Jun;296:100349. doi: 10.1016/j.jbc.2021.100349. Epub 2021 Jan 30. J Biol Chem. 2021. PMID: 33524394 Free PMC article.
Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhibitors.
Gehling VS, McGrath JP, Duplessis M, Khanna A, Brucelle F, Vaswani RG, Côté A, Stuckey J, Watson V, Cummings RT, Balasubramanian S, Iyer P, Sawant P, Good AC, Albrecht BK, Harmange JC, Audia JE, Bellon SF, Trojer P, Levell JR. Gehling VS, et al. Among authors: khanna a. ACS Med Chem Lett. 2020 May 6;11(6):1213-1220. doi: 10.1021/acsmedchemlett.0c00060. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32551003 Free PMC article.
Angiotensin II and Thromboembolism-Reading the Fine Print.
Kotani Y, Khanna AK. Kotani Y, et al. Among authors: khanna ak. Crit Care Med. 2024 Dec 1;52(12):1981-1985. doi: 10.1097/CCM.0000000000006468. Epub 2024 Nov 14. Crit Care Med. 2024. PMID: 39637267 No abstract available.
Preferences and attitudes on acetate- versus lactate-buffered crystalloid solutions for intravenous fluid therapy-An international survey.
Ellekjaer KL, Sivapalan P, Myatra SN, Grønningsæter L, Hästbacka J, Young PJ, Boyle AJ, Ostermann M, Pfortmueller CA, Jovaišienė I, De Waele J, Reintam Blaser A, Al-Fares A, Khanna AK, Arabi YM, Fujii T, Keus E, Mer M, Alshamsi F, Cronhjort M, Perner A, Møller MH. Ellekjaer KL, et al. Among authors: khanna ak. Acta Anaesthesiol Scand. 2025 Jan;69(1):e14553. doi: 10.1111/aas.14553. Acta Anaesthesiol Scand. 2025. PMID: 39627945
Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications: A Randomized Pragmatic Trial.
Ho PM, Glorioso TJ, Allen LA, Blankenhorn R, Glasgow RE, Grunwald GK, Khanna A, Magid DJ, Marrs JC, Novins-Montague S, Orlando S, Peterson P, Plomondon ME, Sandy LM, Saseen JJ, Trinkley KE, Vaughn S, Waughtal J, Bull S. Ho PM, et al. Among authors: khanna a. JAMA. 2024 Dec 2:e2421739. doi: 10.1001/jama.2024.21739. Online ahead of print. JAMA. 2024. PMID: 39621340
International cross-sectional survey on current and updated definitions of intra-abdominal hypertension and abdominal compartment syndrome.
Nasa P, Wise RD, Smit M, Acosta S, D'Amours S, Beaubien-Souligny W, Bodnar Z, Coccolini F, Dangayach NS, Dabrowski W, Duchesne J, Ejike JC, Augustin G, De Keulenaer B, Kirkpatrick AW, Khanna AK, Kimball E, Koratala A, Lee RK, Leppaniemi A, Lerma EV, Marmolejo V, Meraz-Munoz A, Myatra SN, Niven D, Olvera C, Ordoñez C, Petro C, Pereira BM, Ronco C, Regli A, Roberts DJ, Rola P, Rosen M, Shrestha GS, Sugrue M, Velez JCQ, Wald R, De Waele J, Reintam Blaser A, Malbrain MLNG. Nasa P, et al. Among authors: khanna ak. World J Emerg Surg. 2024 Nov 29;19(1):39. doi: 10.1186/s13017-024-00564-5. World J Emerg Surg. 2024. PMID: 39609850 Free PMC article.
1,682 results