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Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance.
Scolaro T, Manco M, Pecqueux M, Amorim R, Trotta R, Van Acker HH, Van Haele M, Shirgaonkar N, Naulaerts S, Daniluk J, Prenen F, Varamo C, Ponti D, Doglioni G, Ferreira Campos AM, Fernandez Garcia J, Radenkovic S, Rouhi P, Beatovic A, Wang L, Wang Y, Tzoumpa A, Antoranz A, Sargsian A, Di Matteo M, Berardi E, Goveia J, Ghesquière B, Roskams T, Soenen S, Voets T, Manshian B, Fendt SM, Carmeliet P, Garg AD, DasGupta R, Topal B, Mazzone M. Scolaro T, et al. Among authors: wang l, wang y. Nat Cancer. 2024 Aug;5(8):1206-1226. doi: 10.1038/s43018-024-00771-8. Epub 2024 Jun 6. Nat Cancer. 2024. PMID: 38844817 Free PMC article.
MANCR lncRNA Modulates Cell-Cycle Progression and Metastasis by Cis-Regulation of Nuclear Rho-GEF.
Singh DK, Cong Z, Song YJ, Liu M, Chaudhary R, Liu D, Wang Y, Prasanth R, K C R, Lizarazo S, Akhnoukh M, Gholamalamdari O, Moitra A, Jenkins LM, Bhargava R, Nelson ER, Van Bortle K, Prasanth SG, Prasanth KV. Singh DK, et al. Among authors: wang y. Mol Cell Biol. 2024;44(9):372-390. doi: 10.1080/10985549.2024.2383773. Epub 2024 Aug 12. Mol Cell Biol. 2024. PMID: 39133105
The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple- negative breast cancer.
Nelczyk AT, Ma L, Gupta AD, Gamage HEV, McHenry MT, Henn MA, Kadiri M, Wang Y, Krawczynska N, Bendre S, He S, Shahoei SH, Madak-Erdogan Z, Hsiao SH, Saleh T, Carpenter V, Gewirtz DA, Spinella MJ, Nelson ER. Nelczyk AT, et al. Among authors: wang y. Biochim Biophys Acta Mol Basis Dis. 2022 Nov 1;1868(11):166515. doi: 10.1016/j.bbadis.2022.166515. Epub 2022 Aug 4. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35932893 Free PMC article.
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