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Structural Modification and Biological Evaluation of 2,8-Disubstituted Adenine and Its Nucleosides as A2A Adenosine Receptor Antagonists: Exploring the Roles of Ribose at Adenosine Receptors.
Kim G, Jarhad DB, Lee G, Kim G, Hou X, Yu J, Lee CS, Warnick E, Gao ZG, Ahn SY, Kwak D, Park K, Lee SD, Park TU, Jung SY, Lee JH, Choi JR, Kim M, Kim D, Kim B, Jacobson KA, Jeong LS. Kim G, et al. Among authors: jarhad db. J Med Chem. 2024 Jun 27;67(12):10490-10507. doi: 10.1021/acs.jmedchem.4c01003. Epub 2024 Jun 6. J Med Chem. 2024. PMID: 38845345
Correction to "Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A2A/A3 Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity".
Kim G, Hou X, Byun WS, Kim G, Jarhad DB, Lee G, Hyun YE, Yu J, Lee CS, Qu S, Warnick E, Gao ZG, Kim JY, Ji S, Shin H, Choi JR, Jacobson KA, Lee HW, Lee SK, Jeong LS. Kim G, et al. Among authors: jarhad db. J Med Chem. 2024 Feb 8;67(3):2236. doi: 10.1021/acs.jmedchem.3c02442. Epub 2024 Jan 23. J Med Chem. 2024. PMID: 38259147 Free PMC article. No abstract available.
Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A2A/A3 Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity.
Kim G, Hou X, Byun WS, Kim G, Jarhad DB, Lee G, Hyun YE, Yu J, Lee CS, Qu S, Warnick E, Gao ZG, Kim JY, Ji S, Shin H, Choi JR, Jacobson KA, Lee HW, Lee SK, Jeong LS. Kim G, et al. Among authors: jarhad db. J Med Chem. 2023 Sep 14;66(17):12249-12265. doi: 10.1021/acs.jmedchem.3c00806. Epub 2023 Aug 21. J Med Chem. 2023. PMID: 37603705 Free PMC article.
GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A2A Adenosine Receptor.
Shiriaeva A, Park D, Kim G, Lee Y, Hou X, Jarhad DB, Kim G, Yu J, Hyun YE, Kim W, Gao ZG, Jacobson KA, Han GW, Stevens RC, Jeong LS, Choi S, Cherezov V. Shiriaeva A, et al. Among authors: jarhad db. J Med Chem. 2022 Sep 8;65(17):11648-11657. doi: 10.1021/acs.jmedchem.2c00462. Epub 2022 Aug 17. J Med Chem. 2022. PMID: 35977382 Free PMC article.
6'-β-Fluoro-Homoaristeromycin and 6'-Fluoro-Homoneplanocin A Are Potent Inhibitors of Chikungunya Virus Replication through Their Direct Effect on Viral Nonstructural Protein 1.
Kovacikova K, Morren BM, Tas A, Albulescu IC, van Rijswijk R, Jarhad DB, Shin YS, Jang MH, Kim G, Lee HW, Jeong LS, Snijder EJ, van Hemert MJ. Kovacikova K, et al. Among authors: jarhad db. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e02532-19. doi: 10.1128/AAC.02532-19. Print 2020 Mar 24. Antimicrob Agents Chemother. 2020. PMID: 31964798 Free PMC article.
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