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Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn's Disease.
Dennison TW, Edgar RD, Payne F, Nayak KM, Ross ADB, Cenier A, Glemas C, Giachero F, Foster AR, Harris R, Kraiczy J, Salvestrini C, Stavrou G, Torrente F, Brook K, Trayers C, Elmentaite R, Youssef G, Tél B, Winton DJ, Skoufou-Papoutsaki N, Adler S, Bufler P, Azabdaftari A, Jenke A, G N, Thomas N, Miele E, Al-Mohammad A, Guarda G, Kugathasan S, Venkateswaran S, Clatworthy MR, Castro-Dopico T, Suchanek O, Strisciuglio C, Gasparetto M, Lee S, Xu X, Bello E, Han N, Zerbino DR, Teichmann SA, Nys J, Heuschkel R, Perrone F, Zilbauer M. Dennison TW, et al. Among authors: zilbauer m. Gut. 2024 Aug 8;73(9):1464-1477. doi: 10.1136/gutjnl-2024-332043. Gut. 2024. PMID: 38857990 Free PMC article.
DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development.
Kraiczy J, Nayak KM, Howell KJ, Ross A, Forbester J, Salvestrini C, Mustata R, Perkins S, Andersson-Rolf A, Leenen E, Liebert A, Vallier L, Rosenstiel PC, Stegle O, Dougan G, Heuschkel R, Koo BK, Zilbauer M. Kraiczy J, et al. Among authors: zilbauer m. Gut. 2019 Jan;68(1):49-61. doi: 10.1136/gutjnl-2017-314817. Epub 2017 Nov 15. Gut. 2019. PMID: 29141958 Free PMC article.
Epigenetics in inflammatory bowel disease.
Jenke AC, Zilbauer M. Jenke AC, et al. Among authors: zilbauer m. Curr Opin Gastroenterol. 2012 Nov;28(6):577-84. doi: 10.1097/MOG.0b013e328357336b. Curr Opin Gastroenterol. 2012. PMID: 23041674 Review.
Transcription and DNA Methylation Patterns of Blood-Derived CD8+ T Cells Are Associated With Age and Inflammatory Bowel Disease But Do Not Predict Prognosis.
Gasparetto M, Payne F, Nayak K, Kraiczy J, Glemas C, Philip-McKenzie Y, Ross A, Edgar RD, Zerbino DR, Salvestrini C, Torrente F, Ventham NT, Kalla R, Satsangi J, Sarkies P, Heuschkel R, Zilbauer M. Gasparetto M, et al. Among authors: zilbauer m. Gastroenterology. 2021 Jan;160(1):232-244.e7. doi: 10.1053/j.gastro.2020.08.017. Epub 2020 Aug 16. Gastroenterology. 2021. PMID: 32814113 Free PMC article.
Biobanking of human gut organoids for translational research.
Perrone F, Zilbauer M. Perrone F, et al. Among authors: zilbauer m. Exp Mol Med. 2021 Oct;53(10):1451-1458. doi: 10.1038/s12276-021-00606-x. Epub 2021 Oct 18. Exp Mol Med. 2021. PMID: 34663935 Free PMC article. Review.
91 results