Metzloff AE - Search Results

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High-Throughput In Vivo Screening Identifies Differential Influences on mRNA Lipid Nanoparticle Immune Cell Delivery by Administration Route.

Hamilton AG, Swingle KL, Thatte AS, Mukalel AJ, Safford HC, Billingsley MM, El-Mayta RD, Han X, Nachod BE, Joseph RA, Metzloff AE, Mitchell MJ. Hamilton AG, et al. Among authors: metzloff ae. ACS Nano. 2024 Jun 25;18(25):16151-16165. doi: 10.1021/acsnano.4c01171. Epub 2024 Jun 11. ACS Nano. 2024. PMID: 38861479

Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy.

Metzloff AE, Padilla MS, Gong N, Billingsley MM, Han X, Merolle M, Mai D, Figueroa-Espada CG, Thatte AS, Haley RM, Mukalel AJ, Hamilton AG, Alameh MG, Weissman D, Sheppard NC, June CH, Mitchell MJ. Metzloff AE, et al. Adv Mater. 2024 Jun;36(26):e2313226. doi: 10.1002/adma.202313226. Epub 2024 Mar 15. Adv Mater. 2024. PMID: 38419362

In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism.

Billingsley MM, Gong N, Mukalel AJ, Thatte AS, El-Mayta R, Patel SK, Metzloff AE, Swingle KL, Han X, Xue L, Hamilton AG, Safford HC, Alameh MG, Papp TE, Parhiz H, Weissman D, Mitchell MJ. Billingsley MM, et al. Among authors: metzloff ae. Small. 2024 Mar;20(11):e2304378. doi: 10.1002/smll.202304378. Epub 2023 Dec 10. Small. 2024. PMID: 38072809

In situ PEGylation of CAR T cells alleviates cytokine release syndrome and neurotoxicity.

Gong N, Han X, Xue L, El-Mayta R, Metzloff AE, Billingsley MM, Hamilton AG, Mitchell MJ. Gong N, et al. Among authors: metzloff ae. Nat Mater. 2023 Dec;22(12):1571-1580. doi: 10.1038/s41563-023-01646-6. Epub 2023 Sep 11. Nat Mater. 2023. PMID: 37696939

Lighting the way to personalized mRNA immune cell therapies.

Metzloff AE, Billingsley MM, Mitchell MJ. Metzloff AE, et al. Sci Adv. 2022 Feb 25;8(8):eabo2423. doi: 10.1126/sciadv.abo2423. Epub 2022 Feb 23. Sci Adv. 2022. PMID: 35196095 Free PMC article. Review.

Litmus-Body: A Molecularly Targeted Sensor for Cell-Surface pH Measurements.

Kuo JC, Goudge MC, Metzloff AE, Huang LT, Colville MJ, Park S, Zipfel WR, Paszek MJ. Kuo JC, et al. Among authors: metzloff ae. ACS Sens. 2020 Jun 26;5(6):1555-1566. doi: 10.1021/acssensors.9b02080. Epub 2020 May 15. ACS Sens. 2020. PMID: 32337979 Free PMC article.

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