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Initiation of metformin in early pregnancy results in fetal bioaccumulation, growth restriction, and renal dysmorphology in a primate model.
Bolte E, Dean T, Garcia B, Seferovic MD, Sauter K, Hummel G, Bucher M, Li F, Hicks J, Qin X, Suter MA, Barrozo ER, Jochum M, Shope C, Friedman JE, Gannon M, Wesolowski SR, McCurdy CE, Kievit P, Aagaard KM. Bolte E, et al. Among authors: wesolowski sr. Am J Obstet Gynecol. 2024 Sep;231(3):352.e1-352.e16. doi: 10.1016/j.ajog.2024.06.002. Epub 2024 Jun 11. Am J Obstet Gynecol. 2024. PMID: 38871238 Free PMC article.
Developmental origins of NAFLD: a womb with a clue.
Wesolowski SR, Kasmi KC, Jonscher KR, Friedman JE. Wesolowski SR, et al. Nat Rev Gastroenterol Hepatol. 2017 Feb;14(2):81-96. doi: 10.1038/nrgastro.2016.160. Epub 2016 Oct 26. Nat Rev Gastroenterol Hepatol. 2017. PMID: 27780972 Free PMC article. Review.
Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates.
Wesolowski SR, Mulligan CM, Janssen RC, Baker PR 2nd, Bergman BC, D'Alessandro A, Nemkov T, Maclean KN, Jiang H, Dean TA, Takahashi DL, Kievit P, McCurdy CE, Aagaard KM, Friedman JE. Wesolowski SR, et al. Mol Metab. 2018 Dec;18:25-41. doi: 10.1016/j.molmet.2018.09.008. Epub 2018 Sep 28. Mol Metab. 2018. PMID: 30337225 Free PMC article.
Differential effects of intrauterine growth restriction and a hypersinsulinemic-isoglycemic clamp on metabolic pathways and insulin action in the fetal liver.
Jones AK, Brown LD, Rozance PJ, Serkova NJ, Hay WW Jr, Friedman JE, Wesolowski SR. Jones AK, et al. Among authors: wesolowski sr. Am J Physiol Regul Integr Comp Physiol. 2019 May 1;316(5):R427-R440. doi: 10.1152/ajpregu.00359.2018. Epub 2019 Feb 13. Am J Physiol Regul Integr Comp Physiol. 2019. PMID: 30758974 Free PMC article.
Maternal Obesity and Western-Style Diet Impair Fetal and Juvenile Offspring Skeletal Muscle Insulin-Stimulated Glucose Transport in Nonhuman Primates.
Campodonico-Burnett W, Hetrick B, Wesolowski SR, Schenk S, Takahashi DL, Dean TA, Sullivan EL, Kievit P, Gannon M, Aagaard K, Friedman JE, McCurdy CE. Campodonico-Burnett W, et al. Among authors: wesolowski sr. Diabetes. 2020 Jul;69(7):1389-1400. doi: 10.2337/db19-1218. Epub 2020 Apr 30. Diabetes. 2020. PMID: 32354857 Free PMC article.
A Two-Week Insulin Infusion in Intrauterine Growth Restricted Fetal Sheep at 75% Gestation Increases Skeletal Myoblast Replication but Did Not Restore Muscle Mass or Increase Fiber Number.
Chang EI, Hetrick B, Wesolowski SR, McCurdy CE, Rozance PJ, Brown LD. Chang EI, et al. Among authors: wesolowski sr. Front Endocrinol (Lausanne). 2021 Nov 30;12:785242. doi: 10.3389/fendo.2021.785242. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34917036 Free PMC article.
61 results