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328 results

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Page 1
Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases.
Scott DC, Chittori S, Purser N, King MT, Maiwald SA, Churion K, Nourse A, Lee C, Paulo JA, Miller DJ, Elledge SJ, Harper JW, Kleiger G, Schulman BA. Scott DC, et al. Among authors: paulo ja. Nat Commun. 2024 Nov 15;15(1):9899. doi: 10.1038/s41467-024-54126-z. Nat Commun. 2024. PMID: 39548056 Free PMC article.
USP14 inhibition enhances Parkin-independent mitophagy in iNeurons.
Bernardo G, Prado MA, Dashtmian AR, Favaro M, Mauri S, Borsetto A, Marchesan E, Paulo JA, Gygi SP, Finley DJ, Ziviani E. Bernardo G, et al. Among authors: paulo ja. Pharmacol Res. 2024 Oct 30;210:107484. doi: 10.1016/j.phrs.2024.107484. Online ahead of print. Pharmacol Res. 2024. PMID: 39486496 Free article.
Direct mitochondrial import of lactate supports resilient carbohydrate oxidation.
Cluntun AA, Visker JR, Velasco-Silva JN, Lang MJ, Cedeño-Rosario L, Shankar TS, Hamouche R, Ling J, Kim JE, Toshniwal AG, Low HK, Cunningham CN, Carrington J, Catrow JL, Pearce Q, Jeong MY, Bott AJ, Narbona-Pérez ÁJ, Stanley CE, Li Q, Eberhardt DR, Morgan JT, Yadav T, Wells CE, Ramadurai DKA, Swiatek WI, Chaudhuri D, Rothstein JD, Muoio DM, Paulo JA, Gygi SP, Baker SA, Navankasattusas S, Cox JE, Funai K, Drakos SG, Rutter J, Ducker GS. Cluntun AA, et al. Among authors: paulo ja. bioRxiv [Preprint]. 2024 Oct 8:2024.10.07.617073. doi: 10.1101/2024.10.07.617073. bioRxiv. 2024. PMID: 39416192 Free PMC article. Preprint.
Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2.
Scott DC, Dharuman S, Griffith E, Chai SC, Ronnebaum J, King MT, Tangallapally R, Lee C, Gee CT, Yang L, Li Y, Loudon VC, Lee HW, Ochoada J, Miller DJ, Jayasinghe T, Paulo JA, Elledge SJ, Harper JW, Chen T, Lee RE, Schulman BA. Scott DC, et al. Among authors: paulo ja. Nat Commun. 2024 Oct 12;15(1):8829. doi: 10.1038/s41467-024-52966-3. Nat Commun. 2024. PMID: 39396041 Free PMC article.
Structural basis of respiratory complex adaptation to cold temperatures.
Shin YC, Latorre-Muro P, Djurabekova A, Zdorevskyi O, Bennett CF, Burger N, Song K, Xu C, Paulo JA, Gygi SP, Sharma V, Liao M, Puigserver P. Shin YC, et al. Among authors: paulo ja. Cell. 2024 Nov 14;187(23):6584-6598.e17. doi: 10.1016/j.cell.2024.09.029. Epub 2024 Oct 11. Cell. 2024. PMID: 39395414
Achieving a 35-Plex Tandem Mass Tag Reagent Set through Deuterium Incorporation.
Zuniga NR, Frost DC, Kuhn K, Shin M, Whitehouse RL, Wei TY, He Y, Dawson SL, Pike I, Bomgarden RD, Gygi SP, Paulo JA. Zuniga NR, et al. Among authors: paulo ja. J Proteome Res. 2024 Nov 1;23(11):5153-5165. doi: 10.1021/acs.jproteome.4c00668. Epub 2024 Oct 9. J Proteome Res. 2024. PMID: 39380184
328 results