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Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells.
Zwergel C, Aventaggiato M, Garbo S, Di Bello E, Fassari B, Noce B, Castiello C, Lambona C, Barreca F, Rotili D, Fioravanti R, Schmalz T, Weyand M, Niedermeier A, Tripodi M, Colotti G, Steegborn C, Battistelli C, Tafani M, Valente S, Mai A. Zwergel C, et al. Among authors: tripodi m. J Med Chem. 2023 Jul 27;66(14):9622-9641. doi: 10.1021/acs.jmedchem.3c00337. Epub 2023 Jul 13. J Med Chem. 2023. PMID: 37439550 Free PMC article.
HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling.
Terri M, Sandoval P, Bontempi G, Montaldo C, Tomero-Sanz H, de Turris V, Trionfetti F, Pascual-Antón L, Clares-Pedrero I, Battistelli C, Valente S, Zwergel C, Mai A, Rosanò L, Del Pozo MÁ, Sánchez-Álvarez M, Cabañas C, Tripodi M, López-Cabrera M, Strippoli R. Terri M, et al. Among authors: tripodi m. J Exp Clin Cancer Res. 2024 Jan 23;43(1):27. doi: 10.1186/s13046-023-02930-8. J Exp Clin Cancer Res. 2024. PMID: 38254102 Free PMC article.
HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells.
Trionfetti F, Alonzi T, Bontempi G, Terri M, Battistelli C, Montaldo C, Repele F, Rotili D, Valente S, Zwergel C, Matusali G, Maggi F, Goletti D, Tripodi M, Mai A, Strippoli R. Trionfetti F, et al. Among authors: tripodi m. Front Cell Infect Microbiol. 2023 Dec 13;13:1257683. doi: 10.3389/fcimb.2023.1257683. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 38162580 Free PMC article.
Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells.
Di Bello E, Sian V, Bontempi G, Zwergel C, Fioravanti R, Noce B, Castiello C, Tomassi S, Corinti D, Passeri D, Pellicciari R, Mercurio C, Varasi M, Altucci L, Tripodi M, Strippoli R, Nebbioso A, Valente S, Mai A. Di Bello E, et al. Among authors: tripodi m. Eur J Med Chem. 2023 Feb 5;247:115022. doi: 10.1016/j.ejmech.2022.115022. Epub 2022 Dec 15. Eur J Med Chem. 2023. PMID: 36549114
Mechanisms of mesothelial cell response to viral infections: HDAC1-3 inhibition blocks poly(I:C)-induced type I interferon response and modulates the mesenchymal/inflammatory phenotype.
Trionfetti F, Montaldo C, Caiello I, Bontempi G, Terri M, Tiberi M, Marchant V, Domenici A, Menè P, Cordani M, Zwergel C, Prencipe G, Ruiz-Ortega M, Valente S, Mai A, Tripodi M, Strippoli R. Trionfetti F, et al. Among authors: tripodi m. Front Cell Infect Microbiol. 2024 Feb 27;14:1308362. doi: 10.3389/fcimb.2024.1308362. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38476167 Free PMC article.
Nanomedicine for autophagy modulation in cancer therapy: a clinical perspective.
López-Méndez TB, Sánchez-Álvarez M, Trionfetti F, Pedraz JL, Tripodi M, Cordani M, Strippoli R, González-Valdivieso J. López-Méndez TB, et al. Among authors: tripodi m. Cell Biosci. 2023 Mar 4;13(1):44. doi: 10.1186/s13578-023-00986-9. Cell Biosci. 2023. PMID: 36871010 Free PMC article. Review.
344 results