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Page 1
Iron-(Fe3+)-Dependent Reactivation of Telomerase Drives Colorectal Cancers.
Shanmugam R, Majee P, Shi W, Ozturk MB, Vaiyapuri TS, Idzham K, Raju A, Shin SH, Fidan K, Low JL, Chua JYH, Kong YC, Qi OY, Tan E, Chok AY, Seow-En I, Wee I, Macalinao DC, Chong DQ, Chang HY, Lee F, Leow WQ, Murata-Hori M, Xiaoqian Z, Shumei C, Tan CSH, Dasgupta R, Tan IB, Tergaonkar V. Shanmugam R, et al. Among authors: raju a. Cancer Discov. 2024 Oct 4;14(10):1940-1963. doi: 10.1158/2159-8290.CD-23-1379. Cancer Discov. 2024. PMID: 38885349 Free PMC article.
p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain).
Teoh PJ, An O, Chung TH, Vaiyapuri T, Raju A, Hoppe MM, Toh SHM, Wang W, Chan MC, Fullwood MJ, Jeyasekharan AD, Tergaonkar V, Chen L, Yang H, Chng WJ. Teoh PJ, et al. Among authors: raju a. Oncogene. 2022 Apr;41(14):2106-2121. doi: 10.1038/s41388-022-02227-8. Epub 2022 Feb 21. Oncogene. 2022. PMID: 35190641
Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.
Zhang J, Hu Z, Chung HH, Tian Y, Lau KW, Ser Z, Lim YT, Sobota RM, Leong HF, Chen BJ, Yeo CJ, Tan SYX, Kang J, Tan DEK, Sou IF, McClurg UL, Lakshmanan M, Vaiyapuri TS, Raju A, Wong ESM, Tergaonkar V, Rajarethinam R, Pathak E, Tam WL, Tan EY, Tee WW. Zhang J, et al. Among authors: raju a. Nat Commun. 2023 Apr 28;14(1):2439. doi: 10.1038/s41467-023-38132-1. Nat Commun. 2023. PMID: 37117180 Free PMC article.
Tumour microenvironment programming by an RNA-RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma.
Wu L, Zhao Z, Shin YJ, Yin Y, Raju A, Vaiyapuri TS, Idzham K, Son M, Lee Y, Sa JK, Chua JYH, Unal B, Zhai Y, Fan W, Huang L, Hu H, Gunaratne J, Nam DH, Jiang T, Tergaonkar V. Wu L, et al. Among authors: raju a. Nat Cell Biol. 2024 Jun;26(6):1003-1018. doi: 10.1038/s41556-024-01428-5. Epub 2024 Jun 10. Nat Cell Biol. 2024. PMID: 38858501 Free PMC article.
Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth.
Zhang Y, Chen K, Tang SC, Cai Y, Nambu A, See YX, Fu C, Raju A, Lebeau B, Ling Z, Chan JJ, Tay Y, Mutwil M, Lakshmanan M, Tucker-Kellogg G, Chng WJ, Tenen DG, Osato M, Tergaonkar V, Fullwood MJ. Zhang Y, et al. Among authors: raju a. Nat Struct Mol Biol. 2024 Sep 20. doi: 10.1038/s41594-024-01391-7. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 39304765
260 results