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CD28-CD57+ T cells from head and neck cancer patients produce high levels of cytotoxic granules and type II interferon but are not senescent.
Kinney BLC, Brammer B, Kansal V, Parrish CJ, Kissick HT, Liu Y, Saba NF, Buchwald ZS, El-Deiry MW, Patel MR, Boyce BJ, Kaka AS, Gross JH, Baddour HM, Chen AY, Schmitt NC. Kinney BLC, et al. Among authors: kissick ht. Oncoimmunology. 2024 Jun 14;13(1):2367777. doi: 10.1080/2162402X.2024.2367777. eCollection 2024. Oncoimmunology. 2024. PMID: 38887372 Free PMC article.
Pre-operative stereotactic radiosurgery and peri-operative dexamethasone for resectable brain metastases: a two-arm pilot study evaluating clinical outcomes and immunological correlates.
Jansen CS, Pagadala MS, Cardenas MA, Prabhu RS, Goyal S, Zhou C, Chappa P, Vo BT, Ye C, Hopkins B, Zhong J, Klie A, Daniels T, Admassu M, Green I, Pfister NT, Neill SG, Switchenko JM, Prokhnevska N, Hoang KB, Torres MA, Logan S, Olson JJ, Nduom EK, Del Balzo L, Patel K, Burri SH, Asher AL, Wilkinson S, Lake R, Kesarwala AH, Higgins KA, Patel P, Dhere V, Sowalsky AG, Carter H, Khan MK, Kissick H, Buchwald ZS. Jansen CS, et al. Nat Commun. 2024 Oct 14;15(1):8854. doi: 10.1038/s41467-024-53034-6. Nat Commun. 2024. PMID: 39402027 Free PMC article. Clinical Trial.
Differentiation fate of a stem-like CD4 T cell controls immunity to cancer.
Cardenas MA, Prokhnevska N, Sobierajska E, Gregorova P, Medina CB, Valanparambil RM, Greenwald R, DelBalzo L, Bilen MA, Joshi SS, Narayan VM, Master VA, Sanda MG, Kissick HT. Cardenas MA, et al. Among authors: kissick ht. Nature. 2024 Oct 23. doi: 10.1038/s41586-024-08076-7. Online ahead of print. Nature. 2024. PMID: 39443797
Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence.
Strongin Z, Raymond Marchand L, Deleage C, Pampena MB, Cardenas MA, Beusch CM, Hoang TN, Urban EA, Gourves M, Nguyen K, Tharp GK, Lapp S, Rahmberg AR, Harper J, Del Rio Estrada PM, Gonzalez-Navarro M, Torres-Ruiz F, Luna-Villalobos YA, Avila-Rios S, Reyes-Teran G, Sekaly R, Silvestri G, Kulpa DA, Saez-Cirion A, Brenchley JM, Bosinger SE, Gordon DE, Betts MR, Kissick HT, Paiardini M. Strongin Z, et al. Among authors: kissick ht. Nat Immunol. 2024 Jul;25(7):1245-1256. doi: 10.1038/s41590-024-01875-0. Epub 2024 Jun 17. Nat Immunol. 2024. PMID: 38886592
Early generation of a precursor CD8 T cell that can adapt to acute or chronic viral infection.
McManus DT, Valanparambil RM, Medina CB, Hu Y, Scharer CD, Sobierajska E, Chang DY, Wieland A, Lee J, Nasti TH, Hashimoto M, Ross JL, Prokhnevska N, Cardenas MA, Gill AL, Clark EC, Abadie K, Kueh HY, Kaye J, Au-Yeung BB, Kissick HT, Ahmed R. McManus DT, et al. Among authors: kissick ht. Res Sq [Preprint]. 2024 Feb 12:rs.3.rs-3922168. doi: 10.21203/rs.3.rs-3922168/v1. Res Sq. 2024. PMID: 38410458 Free PMC article. Preprint.
Localized high-risk prostate cancer harbors an androgen receptor low subpopulation susceptible to HER2 inhibition.
Wilkinson S, Ku AT, Lis RT, King IM, Low D, Trostel SY, Bright JR, Terrigino NT, Baj A, Fenimore JM, Li C, Vo B, Jansen CS, Ye H, Whitlock NC, Harmon SA, Carrabba NV, Atway R, Lake R, Kissick HT, Pinto PA, Choyke PL, Turkbey B, Dahut WL, Karzai F, Sowalsky AG. Wilkinson S, et al. Among authors: kissick ht. medRxiv [Preprint]. 2024 Feb 11:2024.02.09.24302395. doi: 10.1101/2024.02.09.24302395. medRxiv. 2024. PMID: 38370835 Free PMC article. Preprint.
Characteristics and anatomic location of PD-1+TCF1+ stem-like CD8 T cells in chronic viral infection and cancer.
Im SJ, Obeng RC, Nasti TH, McManus D, Kamphorst AO, Gunisetty S, Prokhnevska N, Carlisle JW, Yu K, Sica GL, Cardozo LE, Gonçalves ANA, Kissick HT, Nakaya HI, Ramalingam SS, Ahmed R. Im SJ, et al. Among authors: kissick ht. Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2221985120. doi: 10.1073/pnas.2221985120. Epub 2023 Oct 2. Proc Natl Acad Sci U S A. 2023. PMID: 37782797 Free PMC article.
76 results