Sarma K - Search Results

1

Intertwining roles of R-loops and G-quadruplexes in DNA repair, transcription and genome organization.

Wulfridge P, Sarma K. Wulfridge P, et al. Among authors: sarma k. Nat Cell Biol. 2024 Jul;26(7):1025-1036. doi: 10.1038/s41556-024-01437-4. Epub 2024 Jun 24. Nat Cell Biol. 2024. PMID: 38914786 Review.

2

Mapping Native R-Loops Genome-wide Using a Targeted Nuclease Approach.

Yan Q, Shields EJ, Bonasio R, Sarma K. Yan Q, et al. Among authors: sarma k. Cell Rep. 2019 Oct 29;29(5):1369-1380.e5. doi: 10.1016/j.celrep.2019.09.052. Cell Rep. 2019. PMID: 31665646 Free PMC article.

3

Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function.

Ren W, Medeiros N, Warneford-Thomson R, Wulfridge P, Yan Q, Bian J, Sidoli S, Garcia BA, Skordalakes E, Joyce E, Bonasio R, Sarma K. Ren W, et al. Among authors: sarma k. Nat Commun. 2020 May 6;11(1):2219. doi: 10.1038/s41467-020-15902-9. Nat Commun. 2020. PMID: 32376827 Free PMC article.

4

A nuclease- and bisulfite-based strategy captures strand-specific R-loops genome-wide.

Wulfridge P, Sarma K. Wulfridge P, et al. Among authors: sarma k. Elife. 2021 Feb 23;10:e65146. doi: 10.7554/eLife.65146. Elife. 2021. PMID: 33620319 Free PMC article.

5

Proximity labeling identifies a repertoire of site-specific R-loop modulators.

Yan Q, Wulfridge P, Doherty J, Fernandez-Luna JL, Real PJ, Tang HY, Sarma K. Yan Q, et al. Among authors: sarma k. Nat Commun. 2022 Jan 10;13(1):53. doi: 10.1038/s41467-021-27722-6. Nat Commun. 2022. PMID: 35013239 Free PMC article.

6

Targeted Nuclease Approaches for Mapping Native R-Loops.

Wulfridge P, Yan Q, Sarma K. Wulfridge P, et al. Among authors: sarma k. Methods Mol Biol. 2022;2528:373-380. doi: 10.1007/978-1-0716-2477-7_25. Methods Mol Biol. 2022. PMID: 35704205

7

ATRX histone binding and helicase activities have distinct roles in neuronal differentiation.

Bieluszewska A, Wulfridge P, Doherty J, Ren W, Sarma K. Bieluszewska A, et al. Among authors: sarma k. Nucleic Acids Res. 2022 Sep 9;50(16):9162-9174. doi: 10.1093/nar/gkac683. Nucleic Acids Res. 2022. PMID: 35998910 Free PMC article.

8

DCAF15 control of cohesin dynamics sustains acute myeloid leukemia.

Grothusen GP, Chang R, Cao Z, Zhou N, Mittal M, Datta A, Wulfridge P, Beer T, Wang B, Zheng N, Tang HY, Sarma K, Greenberg RA, Shi J, Busino L. Grothusen GP, et al. Among authors: sarma k. Nat Commun. 2024 Jul 3;15(1):5604. doi: 10.1038/s41467-024-49882-x. Nat Commun. 2024. PMID: 38961054 Free PMC article.

9

MapR: A Method for Identifying Native R-Loops Genome Wide.

Yan Q, Sarma K. Yan Q, et al. Among authors: sarma k. Curr Protoc Mol Biol. 2020 Mar;130(1):e113. doi: 10.1002/cpmb.113. Curr Protoc Mol Biol. 2020. PMID: 31943854 Free PMC article.

10

TET deficiency perturbs mature B cell homeostasis and promotes oncogenesis associated with accumulation of G-quadruplex and R-loop structures.

Shukla V, Samaniego-Castruita D, Dong Z, González-Avalos E, Yan Q, Sarma K, Rao A. Shukla V, et al. Among authors: sarma k. Nat Immunol. 2022 Jan;23(1):99-108. doi: 10.1038/s41590-021-01087-w. Epub 2021 Dec 22. Nat Immunol. 2022. PMID: 34937926 Free PMC article.

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