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Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical Trials.
Poslunsey MS, Wood MR, Han C, Stauffer SR, Panarese JD, Melancon BJ, Engers JL, Dickerson JW, Peng W, Noetzel MJ, Cho HP, Rodriguez AL, Hopkins CR, Morrison R, Crouch RD, Bridges TM, Blobaum AL, Boutaud O, Daniels JS, Kates MJ, Castelhano A, Rook JM, Niswender CM, Jones CK, Conn PJ, Lindsley CW. Poslunsey MS, et al. Among authors: stauffer sr. ACS Chem Neurosci. 2024 Dec 11. doi: 10.1021/acschemneuro.4c00769. Online ahead of print. ACS Chem Neurosci. 2024. PMID: 39660766
Acquired dysfunction of CFTR underlies cystic fibrosis-like disease of the canine gallbladder.
Gookin JL, Holmes J, Clarke LL, Stauffer SH, Meredith B, Vandewege MW, Torres-Machado N, Friedenberg SG, Seiler GS, Mathews KG, Meurs K. Gookin JL, et al. Among authors: stauffer sh. Am J Physiol Gastrointest Liver Physiol. 2024 Oct 1;327(4):G513-G530. doi: 10.1152/ajpgi.00145.2024. Epub 2024 Jul 23. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 39041675
Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma.
Stauffer S, Roth JS, Hernandez ER, Kowalczyk JT, Sealover NE, Hebron KE, James A, Isanogle KA, Riffle LA, Ileva L, Luo X, Chen JQ, Kedei N, Kortum RL, Lei H, Shern JF, Kalen JD, Edmondson EF, Hall MD, Difilippantonio S, Thiele CJ, Yohe ME. Stauffer S, et al. Cancers (Basel). 2024 Jun 25;16(13):2320. doi: 10.3390/cancers16132320. Cancers (Basel). 2024. PMID: 39001383 Free PMC article.
A Second Drug Binding Site in P2X3.
Thach T, Dhanabalan K, Nandekar PP, Stauffer S, Heisler I, Alvarado S, Snyder J, Subramanian R. Thach T, et al. Among authors: stauffer s. bioRxiv [Preprint]. 2024 Jun 14:2024.06.10.598171. doi: 10.1101/2024.06.10.598171. bioRxiv. 2024. PMID: 38915546 Free PMC article. Preprint.
230 results