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Associations between diabetes-related genetic risk scores and residual beta cell function in type 1 diabetes: the GUTDM1 study.
Fuhri Snethlage CM, Balvers M, Ferwerda B, Rampanelli E, de Groen P, Roep BO, Herrema H, McDonald TJ, van Raalte DH, Weedon MN, Oram RA, Nieuwdorp M, Hanssen NMJ. Fuhri Snethlage CM, et al. Among authors: mcdonald tj. Diabetologia. 2024 Sep;67(9):1865-1876. doi: 10.1007/s00125-024-06204-6. Epub 2024 Jun 26. Diabetologia. 2024. PMID: 38922416 Free PMC article.
Residual β-Cell Function Is Associated With Longer Time in Range in Individuals With Type 1 Diabetes.
Fuhri Snethlage CM, McDonald TJ, Oram RD, de Groen P, Rampanelli E, Schimmel AWM, Holleman F, Siegelaar S, Hoekstra J, Brouwer CB, Knop FK, Verchere CB, van Raalte DH, Roep BO, Nieuwdorp M, Hanssen NMJ. Fuhri Snethlage CM, et al. Among authors: mcdonald tj. Diabetes Care. 2024 Jul 1;47(7):1114-1121. doi: 10.2337/dc23-0776. Diabetes Care. 2024. PMID: 37535870 Free PMC article.
Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis.
Leete P, Oram RA, McDonald TJ, Shields BM, Ziller C; TIGI study team; Hattersley AT, Richardson SJ, Morgan NG. Leete P, et al. Among authors: mcdonald tj. Diabetologia. 2020 Jun;63(6):1258-1267. doi: 10.1007/s00125-020-05115-6. Epub 2020 Mar 15. Diabetologia. 2020. PMID: 32172310 Free PMC article.
Type 1 diabetes can present before the age of 6 months and is characterised by autoimmunity and rapid loss of beta cells.
Johnson MB, Patel KA, De Franco E, Hagopian W, Killian M, McDonald TJ, Tree TIM, Domingo-Vila C, Hudson M, Hammersley S, Dobbs R; EXE-T1D Consortium; Ellard S, Flanagan SE, Hattersley AT, Oram RA. Johnson MB, et al. Among authors: mcdonald tj. Diabetologia. 2020 Dec;63(12):2605-2615. doi: 10.1007/s00125-020-05276-4. Epub 2020 Oct 8. Diabetologia. 2020. PMID: 33029656 Free PMC article.
The HNF4A R76W mutation causes atypical dominant Fanconi syndrome in addition to a β cell phenotype.
Hamilton AJ, Bingham C, McDonald TJ, Cook PR, Caswell RC, Weedon MN, Oram RA, Shields BM, Shepherd M, Inward CD, Hamilton-Shield JP, Kohlhase J, Ellard S, Hattersley AT. Hamilton AJ, et al. Among authors: mcdonald tj. J Med Genet. 2014 Mar;51(3):165-9. doi: 10.1136/jmedgenet-2013-102066. Epub 2013 Nov 27. J Med Genet. 2014. PMID: 24285859 Free PMC article.
588 results