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241 results

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Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease.
Kolic J, Sun WG, Cen HH, Ewald JD, Rogalski JC, Sasaki S, Sun H, Rajesh V, Xia YH, Moravcova R, Skovsø S, Spigelman AF, Manning Fox JE, Lyon J, Beet L, Xia J, Lynn FC, Gloyn AL, Foster LJ, MacDonald PE, Johnson JD. Kolic J, et al. Among authors: gloyn al. Cell Metab. 2024 Jul 2;36(7):1619-1633.e5. doi: 10.1016/j.cmet.2024.06.001. Cell Metab. 2024. PMID: 38959864 Free PMC article.
Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding.
Alghamdi TA, Krentz NAJ, Smith N, Spigelman AF, Rajesh V, Jha A, Ferdaoussi M, Suzuki K, Yang J, Manning Fox JE, Sun H, Sun Z, Gloyn AL, MacDonald PE. Alghamdi TA, et al. Among authors: gloyn al. Mol Metab. 2022 Dec;66:101621. doi: 10.1016/j.molmet.2022.101621. Epub 2022 Oct 26. Mol Metab. 2022. PMID: 36307047 Free PMC article.
Small but mighty: microexons in glucose homeostasis.
Garcia K, Gloyn AL. Garcia K, et al. Among authors: gloyn al. Trends Genet. 2023 Jul;39(7):526-527. doi: 10.1016/j.tig.2023.04.003. Epub 2023 Apr 18. Trends Genet. 2023. PMID: 37080883 Free PMC article.
HumanIslets.com: Improving accessibility, integration, and usability of human research islet data.
Ewald JD, Lu Y, Ellis CE, Worton J, Kolic J, Sasaki S, Zhang D, Dos Santos T, Spigelman AF, Bautista A, Dai XQ, Lyon JG, Smith NP, Wong JM, Rajesh V, Sun H, Sharp SA, Rogalski JC, Moravcova R, Cen HH, Manning Fox JE; HumanIslets.com Consortium; Atlas E, Bruin JE, Mulvihill EE, Verchere CB, Foster LJ, Gloyn AL, Johnson JD, Pepper AR, Lynn FC, Xia J, MacDonald PE. Ewald JD, et al. Among authors: gloyn al. Cell Metab. 2024 Sep 24:S1550-4131(24)00365-6. doi: 10.1016/j.cmet.2024.09.001. Online ahead of print. Cell Metab. 2024. PMID: 39357523
CD39 delineates chimeric antigen receptor regulatory T cell subsets with distinct cytotoxic & regulatory functions against human islets.
Wu X, Chen PI, Whitener RL, MacDougall MS, Coykendall VMN, Yan H, Kim YB, Harper W, Pathak S, Iliopoulou BP, Hestor A, Saunders DC, Spears E, Sévigny J, Maahs DM, Basina M, Sharp SA, Gloyn AL, Powers AC, Kim SK, Jensen KP, Meyer EH. Wu X, et al. Among authors: gloyn al. Front Immunol. 2024 Jun 28;15:1415102. doi: 10.3389/fimmu.2024.1415102. eCollection 2024. Front Immunol. 2024. PMID: 39007132 Free PMC article.
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, Rayner NW, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, Thuillier D, Yengo L, Grallert H, Wahl S, Frånberg M, Strawbridge RJ, Kestler H, Chheda H, Eisele L, Gustafsson S, Steinthorsdottir V, Thorleifsson G, Qi L, Karssen LC, van Leeuwen EM, Willems SM, Li M, Chen H, Fuchsberger C, Kwan P, Ma C, Linderman M, Lu Y, Thomsen SK, Rundle JK, Beer NL, van de Bunt M, Chalisey A, Kang HM, Voight BF, Abecasis GR, Almgren P, Baldassarre D, Balkau B, Benediktsson R, Blüher M, Boeing H, Bonnycastle LL, Bottinger EP, Burtt NP, Carey J, Charpentier G, Chines PS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Doney AS, Dorkhan M, Edkins S, Eriksson JG, Esko T, Eury E, Fadista J, Flannick J, Fontanillas P, Fox C, Franks PW, Gertow K, Gieger C, Gigante B, Gottesman O, Grant GB, Grarup N, Groves CJ, Hassinen M, Have CT, Herder C, Holmen OL, Hreidarsson AB, Humphries SE, Hunter DJ, Jackson AU, Jonsson A, Jørgensen ME, Jørgensen T, Kao WH, Kerrison ND, Kinnunen L, Klopp N, Kong A, Kovacs P, Kraft P, Kravic J, Langford C, Leander K, Liang L, Lichtner P, Lindgren CM, Lindholm E, Linneberg A, Liu CT,… See abstract for full author list ➔ Gaulton KJ, et al. Among authors: gloyn al. Nat Genet. 2015 Dec;47(12):1415-25. doi: 10.1038/ng.3437. Epub 2015 Nov 9. Nat Genet. 2015. PMID: 26551672 Free PMC article.
Electrophysiological characterisation of iPSC-derived human β-like cells and an SLC30A8 disease model.
Jaffredo M, Krentz NAJ, Champon B, Duff CE, Nawaz S, Beer N, Honore C, Clark A, Rorsman P, Lang J, Gloyn AL, Raoux M, Hastoy B. Jaffredo M, et al. Among authors: gloyn al. bioRxiv [Preprint]. 2023 Oct 18:2023.10.17.561014. doi: 10.1101/2023.10.17.561014. bioRxiv. 2023. Update in: Diabetes. 2024 Aug 1;73(8):1255-1265. doi: 10.2337/db23-0776 PMID: 37905040 Free PMC article. Updated. Preprint.
241 results