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A tandem activity-based sensing and labeling strategy reveals antioxidant response element regulation of labile iron pools.
Pezacki AT, Gonciarz RL, Okamura T, Matier CD, Torrente L, Cheng K, Miller SG, Ralle M, Ward NP, DeNicola GM, Renslo AR, Chang CJ. Pezacki AT, et al. Among authors: denicola gm. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2401579121. doi: 10.1073/pnas.2401579121. Epub 2024 Jul 5. Proc Natl Acad Sci U S A. 2024. PMID: 38968123 Free PMC article.
RAS in cellular transformation and senescence.
DeNicola GM, Tuveson DA. DeNicola GM, et al. Eur J Cancer. 2009 Sep;45 Suppl 1:211-6. doi: 10.1016/S0959-8049(09)70036-X. Eur J Cancer. 2009. PMID: 19775620 Review. No abstract available.
C-Raf is required for the initiation of lung cancer by K-Ras(G12D).
Karreth FA, Frese KK, DeNicola GM, Baccarini M, Tuveson DA. Karreth FA, et al. Among authors: denicola gm. Cancer Discov. 2011 Jul;1(2):128-36. doi: 10.1158/2159-8290.CD-10-0044. Epub 2011 May 11. Cancer Discov. 2011. PMID: 22043453 Free PMC article.
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.
Olive KP, Jacobetz MA, Davidson CJ, Gopinathan A, McIntyre D, Honess D, Madhu B, Goldgraben MA, Caldwell ME, Allard D, Frese KK, Denicola G, Feig C, Combs C, Winter SP, Ireland-Zecchini H, Reichelt S, Howat WJ, Chang A, Dhara M, Wang L, Rückert F, Grützmann R, Pilarsky C, Izeradjene K, Hingorani SR, Huang P, Davies SE, Plunkett W, Egorin M, Hruban RH, Whitebread N, McGovern K, Adams J, Iacobuzio-Donahue C, Griffiths J, Tuveson DA. Olive KP, et al. Science. 2009 Jun 12;324(5933):1457-61. doi: 10.1126/science.1171362. Epub 2009 May 21. Science. 2009. PMID: 19460966 Free PMC article.
Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.
Mullarky E, Lucki NC, Beheshti Zavareh R, Anglin JL, Gomes AP, Nicolay BN, Wong JC, Christen S, Takahashi H, Singh PK, Blenis J, Warren JD, Fendt SM, Asara JM, DeNicola GM, Lyssiotis CA, Lairson LL, Cantley LC. Mullarky E, et al. Among authors: denicola gm. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1778-83. doi: 10.1073/pnas.1521548113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831078 Free PMC article.
83 results