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Page 1
Attenuated effector T cells are linked to control of chronic HBV infection.
Heim K, Sagar, Sogukpinar Ö, Llewellyn-Lacey S, Price DA, Emmerich F, Kraft ARM, Cornberg M, Kielbassa S, Knolle P, Wohlleber D, Bengsch B, Boettler T, Neumann-Haefelin C, Thimme R, Hofmann M. Heim K, et al. Among authors: wohlleber d. Nat Immunol. 2024 Sep;25(9):1650-1662. doi: 10.1038/s41590-024-01928-4. Epub 2024 Aug 28. Nat Immunol. 2024. PMID: 39198634 Free PMC article.
A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection.
Bosch M, Kallin N, Donakonda S, Zhang JD, Wintersteller H, Hegenbarth S, Heim K, Ramirez C, Fürst A, Lattouf EI, Feuerherd M, Chattopadhyay S, Kumpesa N, Griesser V, Hoflack JC, Siebourg-Polster J, Mogler C, Swadling L, Pallett LJ, Meiser P, Manske K, de Almeida GP, Kosinska AD, Sandu I, Schneider A, Steinbacher V, Teng Y, Schnabel J, Theis F, Gehring AJ, Boonstra A, Janssen HLA, Vandenbosch M, Cuypers E, Öllinger R, Engleitner T, Rad R, Steiger K, Oxenius A, Lo WL, Klepsch V, Baier G, Holzmann B, Maini MK, Heeren R, Murray PJ, Thimme R, Herrmann C, Protzer U, Böttcher JP, Zehn D, Wohlleber D, Lauer GM, Hofmann M, Luangsay S, Knolle PA. Bosch M, et al. Among authors: wohlleber d. Nature. 2024 Jul;631(8022):867-875. doi: 10.1038/s41586-024-07630-7. Epub 2024 Jul 10. Nature. 2024. PMID: 38987588 Free PMC article.
Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+ T cells.
Winkler F, Hipp AV, Ramirez C, Martin B, Villa M, Neuwirt E, Gorka O, Aerssens J, Johansson SE, Rana N, Llewellyn-Lacey S, Price DA, Panning M, Groß O, Pearce EL, Hermann CM, Schumann K, Hannibal L, Neumann-Haefelin C, Boettler T, Knolle P, Hofmann M, Wohlleber D, Thimme R, Bengsch B. Winkler F, et al. Among authors: wohlleber d. Gut. 2023 Oct;72(10):1971-1984. doi: 10.1136/gutjnl-2022-328734. Epub 2023 Aug 4. Gut. 2023. PMID: 37541771 Free PMC article.
A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity.
Meiser P, Knolle MA, Hirschberger A, de Almeida GP, Bayerl F, Lacher S, Pedde AM, Flommersfeld S, Hönninger J, Stark L, Stögbauer F, Anton M, Wirth M, Wohlleber D, Steiger K, Buchholz VR, Wollenberg B, Zielinski CE, Braren R, Rueckert D, Knolle PA, Kaissis G, Böttcher JP. Meiser P, et al. Among authors: wohlleber d. Cancer Cell. 2023 Aug 14;41(8):1498-1515.e10. doi: 10.1016/j.ccell.2023.06.008. Epub 2023 Jul 13. Cancer Cell. 2023. PMID: 37451271 Free article.
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.
Bayerl F, Meiser P, Donakonda S, Hirschberger A, Lacher SB, Pedde AM, Hermann CD, Elewaut A, Knolle M, Ramsauer L, Rudolph TJ, Grassmann S, Öllinger R, Kirchhammer N, Trefny M, Anton M, Wohlleber D, Höchst B, Zaremba A, Krüger A, Rad R, Obenauf AC, Schadendorf D, Zippelius A, Buchholz VR, Schraml BU, Böttcher JP. Bayerl F, et al. Among authors: wohlleber d. Immunity. 2023 Jun 13;56(6):1341-1358.e11. doi: 10.1016/j.immuni.2023.05.011. Immunity. 2023. PMID: 37315536 Free article.
Hepatitis B Virus Targets Lipid Transport Pathways to Infect Hepatocytes.
Esser K, Cheng X, Wettengel JM, Lucifora J, Hansen-Palmus L, Austen K, Roca Suarez AA, Heintz S, Testoni B, Nebioglu F, Pham MT, Yang S, Zernecke A, Wohlleber D, Ringelhan M, Broxtermann M, Hartmann D, Hüser N, Mergner J, Pichlmair A, Thasler WE, Heikenwalder M, Gasteiger G, Blutke A, Walch A, Knolle PA, Bartenschlager R, Protzer U. Esser K, et al. Among authors: wohlleber d. Cell Mol Gastroenterol Hepatol. 2023;16(2):201-221. doi: 10.1016/j.jcmgh.2023.03.011. Epub 2023 Apr 11. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37054914 Free PMC article.
Gut microbiota promote liver regeneration through hepatic membrane phospholipid biosynthesis.
Yin Y, Sichler A, Ecker J, Laschinger M, Liebisch G, Höring M, Basic M, Bleich A, Zhang XJ, Kübelsbeck L, Plagge J, Scherer E, Wohlleber D, Wang J, Wang Y, Steffani M, Stupakov P, Gärtner Y, Lohöfer F, Mogler C, Friess H, Hartmann D, Holzmann B, Hüser N, Janssen KP. Yin Y, et al. Among authors: wohlleber d. J Hepatol. 2023 Apr;78(4):820-835. doi: 10.1016/j.jhep.2022.12.028. Epub 2023 Jan 18. J Hepatol. 2023. PMID: 36681162
Analysis of Mitochondria by Single-Organelle Resolution.
Harbauer AB, Schneider A, Wohlleber D. Harbauer AB, et al. Among authors: wohlleber d. Annu Rev Anal Chem (Palo Alto Calif). 2022 Jun 13;15(1):1-16. doi: 10.1146/annurev-anchem-061020-111722. Epub 2022 Mar 18. Annu Rev Anal Chem (Palo Alto Calif). 2022. PMID: 35303775 Review.
44 results