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INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death.
Duurland CL, Gunst T, Boer HCD, Bosch MTJVD, Telford BJ, Vos RM, Xie X, Zang M, Wang F, Shao Y, An X, Wang J, Cai J, Bourré L, Pinxteren LAHV, Schaapveld RQJ, Janicot M, Yahyanejad S. Duurland CL, et al. Among authors: wang f, wang j. Oncotarget. 2024 Jul 12;15:470-485. doi: 10.18632/oncotarget.28608. Oncotarget. 2024. PMID: 39007281 Free PMC article.
A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology.
Xu X, Kumari R, Zhou J, Chen J, Mao B, Wang J, Zheng M, Tu X, An X, Chen X, Zhang L, Tian X, Wang H, Dong X, Bao Z, Guo S, Ouyang X, Shang L, Wang F, Yan X, Zhang R, Vries RGJ, Clevers H, Li QX. Xu X, et al. Among authors: wang h, wang f, wang j. PLoS One. 2023 Jan 5;18(1):e0279821. doi: 10.1371/journal.pone.0279821. eCollection 2023. PLoS One. 2023. PMID: 36602988 Free PMC article.
Tumor Purity in Preclinical Mouse Tumor Models.
Qian W, Chen X, Sheng Y, Zhang L, Wang J, Song Z, Li QX, Guo S. Qian W, et al. Among authors: wang j. Cancer Res Commun. 2022 May 10;2(5):353-365. doi: 10.1158/2767-9764.CRC-21-0126. eCollection 2022 May. Cancer Res Commun. 2022. PMID: 36875715 Free PMC article.
ATG-101 Is a Tetravalent PD-L1×4-1BB Bispecific Antibody That Stimulates Antitumor Immunity through PD-L1 Blockade and PD-L1-Directed 4-1BB Activation.
Yuwen H, Wang H, Li T, Ren Y, Zhang YK, Chen P, Sun A, Bian G, Li B, Flowers D, Presler M, Subramanian K, Xue J, Wang J, Lynch K, Mei J, He X, Shan B, Hou B. Yuwen H, et al. Among authors: wang h, wang j. Cancer Res. 2024 May 15;84(10):1680-1698. doi: 10.1158/0008-5472.CAN-23-2701. Cancer Res. 2024. PMID: 38501978 Free PMC article.
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