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Inhibition of hepatic bile salt uptake by Bulevirtide reduces atherosclerosis in Oatp1a1-/-Ldlr-/- mice.
Porteiro B, Roscam Abbing RLP, In Het Panhuis W, de Waart DR, Duijst S, Bolt I, Vogels EW, Levels JHM, Bosmans LA, Vos WG, Oude Elferink RPJ, Lutgens E, van de Graaf SFJ. Porteiro B, et al. Among authors: de waart dr. J Lipid Res. 2024 Aug;65(8):100594. doi: 10.1016/j.jlr.2024.100594. Epub 2024 Jul 14. J Lipid Res. 2024. PMID: 39009243 Free PMC article.
Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice.
Slijepcevic D, Roscam Abbing RLP, Katafuchi T, Blank A, Donkers JM, van Hoppe S, de Waart DR, Tolenaars D, van der Meer JHM, Wildenberg M, Beuers U, Oude Elferink RPJ, Schinkel AH, van de Graaf SFJ. Slijepcevic D, et al. Among authors: de waart dr. Hepatology. 2017 Nov;66(5):1631-1643. doi: 10.1002/hep.29251. Epub 2017 Sep 29. Hepatology. 2017. PMID: 28498614 Free PMC article.
NTCP deficiency in mice protects against obesity and hepatosteatosis.
Donkers JM, Kooijman S, Slijepcevic D, Kunst RF, Roscam Abbing RL, Haazen L, de Waart DR, Levels JH, Schoonjans K, Rensen PC, Oude Elferink RP, van de Graaf SF. Donkers JM, et al. Among authors: de waart dr. JCI Insight. 2019 Jun 25;5(14):e127197. doi: 10.1172/jci.insight.127197. JCI Insight. 2019. PMID: 31237863 Free PMC article.
Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice.
Slijepcevic D, Kaufman C, Wichers CG, Gilglioni EH, Lempp FA, Duijst S, de Waart DR, Elferink RP, Mier W, Stieger B, Beuers U, Urban S, van de Graaf SF. Slijepcevic D, et al. Among authors: de waart dr. Hepatology. 2015 Jul;62(1):207-19. doi: 10.1002/hep.27694. Epub 2015 May 8. Hepatology. 2015. PMID: 25641256 Free PMC article.
99 results