Worley PF - Search Results

1

The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation.

Zhou J, Chuang Y', Redding-Ochoa J, Zhang R, Platero AJ, Barrett AH, Troncoso JC, Worley PF, Zhang W. Zhou J, et al. Among authors: worley pf. Nat Cell Biol. 2024 Aug;26(8):1274-1286. doi: 10.1038/s41556-024-01461-4. Epub 2024 Jul 15. Nat Cell Biol. 2024. PMID: 39009640

2

Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation.

Wu J, Petralia RS, Kurushima H, Patel H, Jung MY, Volk L, Chowdhury S, Shepherd JD, Dehoff M, Li Y, Kuhl D, Huganir RL, Price DL, Scannevin R, Troncoso JC, Wong PC, Worley PF. Wu J, et al. Among authors: worley pf. Cell. 2011 Oct 28;147(3):615-28. doi: 10.1016/j.cell.2011.09.036. Cell. 2011. PMID: 22036569 Free PMC article.

3

Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation.

Zhang W, Chuang YA, Na Y, Ye Z, Yang L, Lin R, Zhou J, Wu J, Qiu J, Savonenko A, Leahy DJ, Huganir R, Linden DJ, Worley PF. Zhang W, et al. Among authors: worley pf. Mol Cell. 2019 Jul 11;75(1):13-25.e5. doi: 10.1016/j.molcel.2019.05.004. Epub 2019 May 28. Mol Cell. 2019. PMID: 31151856 Free PMC article.

4

Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions.

Engelender S, Kaminsky Z, Guo X, Sharp AH, Amaravi RK, Kleiderlein JJ, Margolis RL, Troncoso JC, Lanahan AA, Worley PF, Dawson VL, Dawson TM, Ross CA. Engelender S, et al. Among authors: worley pf. Nat Genet. 1999 May;22(1):110-4. doi: 10.1038/8820. Nat Genet. 1999. PMID: 10319874

5

Structural basis of arc binding to synaptic proteins: implications for cognitive disease.

Zhang W, Wu J, Ward MD, Yang S, Chuang YA, Xiao M, Li R, Leahy DJ, Worley PF. Zhang W, et al. Among authors: worley pf. Neuron. 2015 Apr 22;86(2):490-500. doi: 10.1016/j.neuron.2015.03.030. Epub 2015 Apr 9. Neuron. 2015. PMID: 25864631 Free PMC article.

6

Rheb mediates neuronal-activity-induced mitochondrial energetics through mTORC1-independent PDH activation.

Yang W, Pang D, Chen M, Du C, Jia L, Wang L, He Y, Jiang W, Luo L, Yu Z, Mao M, Yuan Q, Tang P, Xia X, Cui Y, Jing B, Platero A, Liu Y, Wei Y, Worley PF, Xiao B. Yang W, et al. Among authors: worley pf. Dev Cell. 2021 Mar 22;56(6):811-825.e6. doi: 10.1016/j.devcel.2021.02.022. Epub 2021 Mar 15. Dev Cell. 2021. PMID: 33725483 Free PMC article.

7

Alzheimer's therapeutics: translation of preclinical science to clinical drug development.

Savonenko AV, Melnikova T, Hiatt A, Li T, Worley PF, Troncoso JC, Wong PC, Price DL. Savonenko AV, et al. Among authors: worley pf. Neuropsychopharmacology. 2012 Jan;37(1):261-77. doi: 10.1038/npp.2011.211. Epub 2011 Sep 21. Neuropsychopharmacology. 2012. PMID: 21937983 Free PMC article. Review.

8

Persistently Elevated mTOR Complex 1-S6 Kinase 1 Disrupts DARPP-32-Dependent D₁ Dopamine Receptor Signaling and Behaviors.

Lin R, Learman LN, Na CH, Renuse S, Chen KT, Chen PY, Lee GH, Xiao B, Resnick SM, Troncoso JC, Szumlinski KK, Linden DJ, Park JM, Savonenko A, Pandey A, Worley PF. Lin R, et al. Among authors: worley pf. Biol Psychiatry. 2021 Jun 1;89(11):1058-1072. doi: 10.1016/j.biopsych.2020.10.012. Epub 2020 Oct 27. Biol Psychiatry. 2021. PMID: 33353667 Free PMC article.

9

NPTX2 and cognitive dysfunction in Alzheimer's Disease.

Xiao MF, Xu D, Craig MT, Pelkey KA, Chien CC, Shi Y, Zhang J, Resnick S, Pletnikova O, Salmon D, Brewer J, Edland S, Wegiel J, Tycko B, Savonenko A, Reeves RH, Troncoso JC, McBain CJ, Galasko D, Worley PF. Xiao MF, et al. Among authors: worley pf. Elife. 2017 Mar 23;6:e23798. doi: 10.7554/eLife.23798. Elife. 2017. PMID: 28440221 Free PMC article.

10

The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration.

Zhou J, Wade SD, Graykowski D, Xiao MF, Zhao B, Giannini LAA, Hanson JE, van Swieten JC, Sheng M, Worley PF, Dejanovic B. Zhou J, et al. Among authors: worley pf. Sci Transl Med. 2023 Mar 29;15(689):eadf0141. doi: 10.1126/scitranslmed.adf0141. Epub 2023 Mar 29. Sci Transl Med. 2023. PMID: 36989373 Free PMC article.

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