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Page 1
Molecular dissection of cobra venom highlights heparinoids as an antidote for spitting cobra envenoming.
Du TY, Hall SR, Chung F, Kurdyukov S, Crittenden E, Patel K, Dawson CA, Westhorpe AP, Bartlett KE, Rasmussen SA, Moreno CL, Denes CE, Albulescu LO, Marriott AE, Mackay JP, Wilkinson MC, Gutiérrez JM, Casewell NR, Neely GG. Du TY, et al. Among authors: neely gg. Sci Transl Med. 2024 Jul 17;16(756):eadk4802. doi: 10.1126/scitranslmed.adk4802. Epub 2024 Jul 17. Sci Transl Med. 2024. PMID: 39018365
The structural conformation of the tachykinin domain drives the anti-tumoural activity of an octopus peptide in melanoma BRAFV600E.
Moral-Sanz J, Fernandez-Rojo MA, Colmenarejo G, Kurdyukov S, Brust A, Ragnarsson L, Andersson Å, Vila SF, Cabezas-Sainz P, Wilhelm P, Vela-Sebastián A, Fernández-Carrasco I, Chin YKY, López-Mancheño Y, Smallwood TB, Clark RJ, Fry BG, King GF, Ramm GA, Alewood PF, Lewis RJ, Mulvenna JP, Boyle GM, Sanchez LE, Neely GG, Miles JJ, Ikonomopoulou MP. Moral-Sanz J, et al. Among authors: neely gg. Br J Pharmacol. 2022 Oct;179(20):4878-4896. doi: 10.1111/bph.15923. Epub 2022 Jul 29. Br J Pharmacol. 2022. PMID: 35818835 Free article.
The VEGAS Platform Is Unsuitable for Mammalian Directed Evolution.
Denes CE, Cole AJ, Tran MTN, Mohd Khalid MKN, Hewitt AW, Hesselson D, Neely GG. Denes CE, et al. Among authors: neely gg. ACS Synth Biol. 2022 Oct 21;11(10):3544-3549. doi: 10.1021/acssynbio.2c00460. Epub 2022 Oct 11. ACS Synth Biol. 2022. PMID: 36219697
Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs.
Loo L, Waller MA, Moreno CL, Cole AJ, Stella AO, Pop OT, Jochum AK, Ali OH, Denes CE, Hamoudi Z, Chung F, Aggarwal A, Low JKK, Patel K, Siddiquee R, Kang T, Mathivanan S, Mackay JP, Jochum W, Flatz L, Hesselson D, Turville S, Neely GG. Loo L, et al. Among authors: neely gg. PLoS Biol. 2023 Feb 9;21(2):e3001967. doi: 10.1371/journal.pbio.3001967. eCollection 2023 Feb. PLoS Biol. 2023. PMID: 36757924 Free PMC article.
Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function.
Jami S, Deuis JR, Klasfauseweh T, Cheng X, Kurdyukov S, Chung F, Okorokov AL, Li S, Zhang J, Cristofori-Armstrong B, Israel MR, Ju RJ, Robinson SD, Zhao P, Ragnarsson L, Andersson Å, Tran P, Schendel V, McMahon KL, Tran HNT, Chin YK, Zhu Y, Liu J, Crawford T, Purushothamvasan S, Habib AM, Andersson DA, Rash LD, Wood JN, Zhao J, Stehbens SJ, Mobli M, Leffler A, Jiang D, Cox JJ, Waxman SG, Dib-Hajj SD, Neely GG, Durek T, Vetter I. Jami S, et al. Among authors: neely gg. Nat Commun. 2023 Apr 28;14(1):2442. doi: 10.1038/s41467-023-37963-2. Nat Commun. 2023. PMID: 37117223 Free PMC article.
104 results